Y-chromosome and autosomal STR diversity in four proximate settlements in Central Anatolia

Alakoç, Yeşim Doğan; Gökçümen, Ömer; Tuğ, Ayşim; Gülteki̇n, Timur; Güleç, Erksin; Schurr, Theodore G.

doi:10.1016/j.fsigen.2010.01.016

Cited by 13 publications

(9 citation statements)

References 9 publications

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“…Our approach for determining haplogroup distributions comprised the following steps: (i) extracting the raw haplogroup data (absolute numbers) from each study; (ii) standardizing the nomenclature for each haplogroup [International Society of Genetic Genealogy (2016)]; (iii) merging data from different studies and summing the absolute frequency of each haplogroup for each population/sub-population; and (iv) calculating relative frequencies (%) of each haplogroup for each population/sub-population, using the merged data. Due to the fact that a key study containing Turkish and Kurdish samples from Central Anatolia[29] did not provide specific subclades for haplogroup E1b1b, a validated haplogroup prediction tool was used for determining those[16,17]. Y-haplogroup frequencies for Cypriots and for all other relevant populations can be found in S6 Table and S7 Table, respectively.…”

Section: Methodsmentioning

confidence: 99%

Y-chromosomal analysis of Greek Cypriots reveals a primarily common pre-Ottoman paternal ancestry with Turkish Cypriots

et al. 2017

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Genetics can provide invaluable information on the ancestry of the current inhabitants of Cyprus. A Y-chromosome analysis was performed to (i) determine paternal ancestry among the Greek Cypriot (GCy) community in the context of the Central and Eastern Mediterranean and the Near East; and (ii) identify genetic similarities and differences between Greek Cypriots (GCy) and Turkish Cypriots (TCy). Our haplotype-based analysis has revealed that GCy and TCy patrilineages derive primarily from a single gene pool and show very close genetic affinity (low genetic differentiation) to Calabrian Italian and Lebanese patrilineages. In terms of more recent (past millennium) ancestry, as indicated by Y-haplotype sharing, GCy and TCy share much more haplotypes between them than with any surrounding population (7–8% of total haplotypes shared), while TCy also share around 3% of haplotypes with mainland Turks, and to a lesser extent with North Africans. In terms of Y-haplogroup frequencies, again GCy and TCy show very similar distributions, with the predominant haplogroups in both being J2a-M410, E-M78, and G2-P287. Overall, GCy also have a similar Y-haplogroup distribution to non-Turkic Anatolian and Southwest Caucasian populations, as well as Cretan Greeks. TCy show a slight shift towards Turkish populations, due to the presence of Eastern Eurasian (some of which of possible Ottoman origin) Y-haplogroups. Overall, the Y-chromosome analysis performed, using both Y-STR haplotype and binary Y-haplogroup data puts Cypriot in the middle of a genetic continuum stretching from the Levant to Southeast Europe and reveals that despite some differences in haplotype sharing and haplogroup structure, Greek Cypriots and Turkish Cypriots share primarily a common pre-Ottoman paternal ancestry.

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Section: Methodsmentioning

confidence: 99%

Y-chromosomal analysis of Greek Cypriots reveals a primarily common pre-Ottoman paternal ancestry with Turkish Cypriots

et al. 2017

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“…The genotyping results and the subjects' paternal province and their city or village of origin when available are listed in Table S2. The dataset used include Middle Easterns (2,720 samples) [10], [11], [12], [13], [14], Central/South Asians (1,335 samples) [15], [16], [17], [18], East Asians (1,029 samples) [15], [19], Caucasians (1,525 samples) [20], West Russians (545 samples) [21], Europeans (1,123 samples) [21], [22], [23], [24], [25], and Africans (222 samples) [26], [27]. More details on the analyzed samples are listed in Table S3.…”

Section: Methodsmentioning

confidence: 99%

Afghanistan's Ethnic Groups Share a Y-Chromosomal Heritage Structured by Historical Events

Haber

Platt²,

Bonab

et al. 2012

PLoS ONE

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Afghanistan has held a strategic position throughout history. It has been inhabited since the Paleolithic and later became a crossroad for expanding civilizations and empires. Afghanistan's location, history, and diverse ethnic groups present a unique opportunity to explore how nations and ethnic groups emerged, and how major cultural evolutions and technological developments in human history have influenced modern population structures. In this study we have analyzed, for the first time, the four major ethnic groups in present-day Afghanistan: Hazara, Pashtun, Tajik, and Uzbek, using 52 binary markers and 19 short tandem repeats on the non-recombinant segment of the Y-chromosome. A total of 204 Afghan samples were investigated along with more than 8,500 samples from surrounding populations important to Afghanistan's history through migrations and conquests, including Iranians, Greeks, Indians, Middle Easterners, East Europeans, and East Asians. Our results suggest that all current Afghans largely share a heritage derived from a common unstructured ancestral population that could have emerged during the Neolithic revolution and the formation of the first farming communities. Our results also indicate that inter-Afghan differentiation started during the Bronze Age, probably driven by the formation of the first civilizations in the region. Later migrations and invasions into the region have been assimilated differentially among the ethnic groups, increasing inter-population genetic differences, and giving the Afghans a unique genetic diversity in Central Asia.

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“…In principle, if these measures were not significantly higher than 0, then this would indicate that most of the variation is found within the settlements and the variation structured between groups is not significant. In the case of Yuksekyer, the R ST measures reached significance ( p < .01; Alakoc et al 2010). The positive R ST values indicated that the among‐population variation was significant and suggested that male gene flow between settlements was minimal, at best.…”

Section: Local Identities and Genetic Barriersmentioning

confidence: 93%

“…Here, we present new genetic data from these loci for the Kizilyer population as well as the mitochondrial DNA (mtDNA) hypervariable I (HVSI) sequence data from Yuksekyer. We have previously published a data announcement article with autosomal and Y‐STR markers for Yuksekyer (Alakoc et al 2010) and included these data in our broader analysis of Anatolian genetic diversity. Because the focus of this article is the interpretation of these data in cultural, historical, and social contexts, most of the methods, the raw genetic data, and the basic quantitative analyses are provided in the Supporting Information.…”

mentioning

confidence: 99%

Biological Ancestries, Kinship Connections, and Projected Identities in Four Central Anatolian Settlements: Insights from Culturally Contextualized Genetic Anthropology

Gökçümen

Gülteki̇n

Alakoç

et al. 2011

American Anthropologist

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Previous population genetics studies in Turkey failed to delineate recent historical and social factors that shaped Anatolian cultural and genetic diversity at the local level. To address this shortcoming, we conducted focused ethnohistorical fieldwork and screened biological samples collected from the Yuksekyer region for mitochondrial, Y chromosome, and autosomal markers and then analyzed the data within an ethnohistorical context. Our results revealed that, at the village level, paternal genetic diversity is structured among settlements, whereas maternal genetic diversity is distributed more homogenously, reflecting the strong patrilineal cultural traditions that transcend larger ethnic and religious structures. Local ancestries and origin myths, rather than ethnic or religious affiliations, delineate the social boundaries and projected identities among the villages. Therefore, we conclude that broad, ethnicity-based sampling is inadequate to capture the genetic signatures of recent social and historical dynamics, which have had a profound influence on contemporary genetic and cultural regional diversity.

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Y-chromosome and autosomal STR diversity in four proximate settlements in Central Anatolia

Cited by 13 publications

References 9 publications

Y-chromosomal analysis of Greek Cypriots reveals a primarily common pre-Ottoman paternal ancestry with Turkish Cypriots

Y-chromosomal analysis of Greek Cypriots reveals a primarily common pre-Ottoman paternal ancestry with Turkish Cypriots

Afghanistan's Ethnic Groups Share a Y-Chromosomal Heritage Structured by Historical Events

Biological Ancestries, Kinship Connections, and Projected Identities in Four Central Anatolian Settlements: Insights from Culturally Contextualized Genetic Anthropology

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