Xxiii. Free and Total Thiamine Contents of Colostrum and Mature Human Milk

Roderuck, Charlotte E.; Williams, Harold H.; Macy, Icie G.

doi:10.1001/archpedi.1945.02020210029005

Cited by 10 publications

(3 citation statements)

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“…Thiamin is present in breast milk mostly as TMP (about 70%) and free thiamin (about 30%), while a negligible amount of TDP has been reported (less than 1%) (Stuetz et al., ,b). The concentration of thiamin is lower in colostrum (1–5 days) and transitional milk (5–13 days) than in mature milk, and the concentration remains constant during the rest of the lactation (Roderuck et al., ; Ford et al., ; Dostalova et al., ). Maternal thiamin intake does not significantly affect the thiamin concentration in breast milk, except in women deficient in the vitamin (Picciano, ; Coats et al., ).…”

Section: Definition/categorymentioning

confidence: 99%

“…Thiamin concentrations in breast milk from healthy mothers of term infants in Western countries are shown in Appendix A. The mean thiamin concentrations in mature breast milk ranged from 0.14 to 0.22 mg/L (midpoint 0.18 mg/L) (Roderuck et al., ; Nail et al., ; Thomas et al., ; Ford et al., ; Dostalova et al., ; Ortega et al., ).…”

Section: Definition/categorymentioning

confidence: 99%

“…()USAn = 6Not supplemented 1.49 ± 0.966 months (mature)208 ± 34Modification of the thiochrome method (Hennessy and Cerecedo ())n = 6 Supplemented Food: 1.56 ± 0.47 Supplements: 1.7 6 months (mature)228 ± 26Roderuck et al. ()USA 2 (2) 5 (5) 6 (6) 6 (6) 6 (6) 6 (6) 9 (9) 7 (7) 7 (7) 6 (6) Day 1 Day 2 Day 3 Day 4 Day 5 Day 6 Day 7 Day 8 Day 9 Day 10 14.8 15.1 16.2 19.6 25.0 35.4 46.5 56.8 77.7 81.2 9.2–20.5 12.4–18.4 12.3–20.8 17.0–24.0 17.2–33.9 23.2–48.6 31.0–62.1 32.0–78.7 58.0–105.2 66.8–102.2 Thiochrome method adapted from Hennessy ()10 (90)45–306 days (mature)14891–18465 (187)15–362 days (mature)14081–227…”

Section: Appendix a – Concentrations Of Thiamin In Breast Milk From Mmentioning

confidence: 99%

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Dietary reference values for thiamin

Turck¹,

Bresson²,

Burlingame³

et al. 2016

EFS2

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Following a request from the European Commission, the EFSA Panel on Dietetic Products, Nutrition and Allergies (NDA) derived dietary reference values (DRVs) for thiamin (vitamin B1). The Panel considers that data from depletion-repletion studies in adults on the amount of dietary thiamin intake associated with the erythrocyte transketolase activity coefficient (aETK) < 1.15, generally considered to reflect an adequate thiamin status, or with the restoration of normal (baseline) erythrocyte transketolase activity, without a sharp increase in urinary thiamin excretion, can be used to estimate thiamin requirement. In the absence of new scientific evidence, the Panel endorses the average requirement (AR) of 0.072 mg/MJ (0.3 mg/1,000 kcal) for all adults proposed by the Scientific Committee for Food (SCF) in 1993 on the basis of one depletion-repletion study, in which both aETK and urinary thiamin excretion were measured. Results from other depletion-repletion studies are in agreement with this value. The Panel agrees on the coefficient of variation of 20% used by the SCF to cover uncertainties related to distribution of thiamin requirements in the general population, and endorses the population reference intake (PRI) of 0.1 mg/MJ (0.4 mg/1,000 kcal) set by the SCF for all adults. The same AR and PRI as for adults, expressed in mg/MJ, are proposed for infants aged 7-11 months, children aged 1 to < 18 years, and during pregnancy and lactation, under the assumption that the relationship between thiamin requirement and energy requirement is the same in all population groups. Acknowledgements: The Panel wishes to thank EFSA member of staff Fanny H eraud for the support provided to this scientific opinion.

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