The nutritional and medicinal benefits of papaya (Carica papaya Linn.) have long been known. Many traditional medical systems, such as Ayurveda, recognise papaya's medicinal potential. Traditional literature has used it to treat fever, swellings, bilious fever, gonorrhoea, eczema, rheumatism, headache, whooping cough, asthma, chickenpox, and bronchitis. A vital nutraceutical agent has been identified after four decades of remarkable research on its biological activity and medical applications. The leaf of Carica papaya Linn. has antibacterial, antipyretic, insecticidal, antimicrobial, and antimolluscan effects. Phytoextraction of heavy metals, phytoremediation of particle pollution, and other modern approaches have been utilised to study leaves. Phytoconstituents and leaf composition have been studied for decades. Carica papaya is used to cure a variety of diseases including malaria, dengue fever, inflammation, and skin infections. The antioxidant and antibacterial activity of C. papaya flowers were first assessed using TLC screening and UV spectroscopy. The extracts were also analysed by TLC and UV-visible spectroscopy. The methanol extract included the greatest alkaloids, flavonoids, saponins, and tannins, according to the screening results. Both chloroform and n-hexane extracts had saponins and tannins, while n-hexane also had steroids and flavonoids. It had flavonoids, tannins, saponins, and phenolic chemicals.