XRD, EDX and FTIR study of the bioactivity of 60S GLASS doped with La and Y under in vitro conditions

Abstract

The aim of the work is the synthesis and study of the bioactivity of sol-gel glass (BG 60S) with molar composition 60 % SiO2, 36 % CaO, 4 % P2O5 and samples doped with La and Y in vitro; studying their structural properties and changes upon contact with a model physiological environment (Kokubo’s SBF), as well as justifying the possibility of their use for tissue regeneration and tissue engineering. According to the results of research, the interaction of synthesized samples with SBF leads to a change in the phase composition and the ratio of amorphous and crystalline components. It is necessary to note long and intensive processes involving CO32– ions for unalloyed and alloyed samples. The appearance of calcium carbonate in the form of vaterite with a simultaneous increase in the calcite content is one of the signs of high bioactivity of the synthesized samples. According to the results of XRD, EDX and FTIR studies after 28 days of soaking in SBF, the predominant surface elements are Ca and P in the composition of hydroxyapatite, and the elemental composition indicates active ion exchange processes according to the theory of bioactive glass dissolution in physiological fluids. The change in the ratio of crystalline phases with the inclusion of mainly one crystalline phase of hydroxopatite within 28 days leads to a better structuredness of the surface of the synthesized samples and indicates that they have osteoconductive properties, can connect with bone tissue and have the appropriate biodegradation ability. The results of the study indicate the promising nature of synthesized materials for tissue regeneration and tissue engineering.

Tailored electrophoretic coatings for enhanced corrosion resistance of 316L stainless steel implants using bioactive glasses

“…33 Following the observations of Kusyak et al , the decrease in the Si content is characteristic of bioactive glass, indicating active processes of ion exchange between the surface and SBF medium. 44…”

Spectral Investigations of 60S Bioactive Glass Modified with La and Y Ions

“…The structure of the obtained 60S bioglass samples was characterized by the XRD as part of the study in ref 30. The amorphous nature of the synthesized samples and the presence of crystalline inclusions of at least two phases, in particular, the weakly crystalline phase of hydroxyapatite Ca 10 (PO 4 ) 6 (OH) 2 and calcite CaCO 3 , were established.…”