XLI.—Bromomethylfurfuraldehyde

Abstract

IN a previous communication (Trans., 1898, 73, 554), i t mas shown by the present authors that certain carbohydrates, when treated with hydrogen bromide in ethereal solution, give an intense and beautiful purple colour. It was suggested that the reaction mould probably be of service i n distinguishing certain typical classes of carbohydrates, and that it might be employed for the detection of these in natural products.The examination of a considerable number of carbohydrates of various classes led to the following goneralisations.1.-With ketohexoses (Izvulose, sorbose), the purple colour appears after a few minutes, and becomes very intense in about one hour ; and substances which, by hydrolysis, are capable of giving rise t o these compounds (cane sugar, inulin) give a similar effect, only rather more slowly, the maximum colour being attnined in about two hours.Z.-HexaZdoses (dextrose, galactose), and substances capable of giving rise to them (milk sugar, maltose, dextrin), show, in the first instance, various shades of yellow, brown, or red, and i t is only after long standing that a purple colour is apparent. This colour, however, never approaches in brilliancy or intensity that obtained with substances mentioned in 1.

Biobased polyesters and other polymers from 2,5-furandicarboxylic acid: a tribute to furan excellency

“…Fittig and Heinzelman 60 published the first study about the synthesis of FDCA in 1876 via dehydration of galactaric acid with fuming hydrobromic acid and a few years later, in 1888, Sohst and Tollens 61 used the isomer saccharic acid on its synthesis. The oxidation of 5-hydroxymethylfurfural (HMF) and derivatives was first reported in 1899, 62 followed by the condensation of glyoxal with dimethyl diglycolate in the presence of sodium methoxide in 1936 63 as alternative approaches for the synthesis of FDCA. However, the development of FDCA synthetic process and related polymers was discontinued since these early studies and was only resumed in the last 10 years.…”

Experimental studies towards optimization of the production of 5-(chloromethyl)furfural (CMF) from glucose in a two-phase reactor

“…This raises the possibility that an optimal system for producing CMF might contain little or no aqueous phase. In fact, in early work in this field, Fenton and Gostling produced BMF [18] and CMF [19] by simple treatment of fructose, sucrose and cellulose with ethereal HBr and HCl, respectively, at room temperature over a period of 12e48 h. Although the yields in these studies were low, no attempt to optimize the reaction under these conditions has been published.…”

Emerging Strategies of Cancer Therapy Based on Ferroptosis

“…[40,41] The Fenton reaction between iron (II or III) and H 2 O 2 has been widely accepted and is described as follows: [40,41] $${\mathrm{italicFe}}^{2+}+H_2{O}_2={\mathrm{italicFe}}^{3+}+·\text{OH}+H{O}^{-}$$ $$F{e}^{3+}+H_2{O}_2=F{e}^{2+}+·OOH+H^{+}$$…”