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Puhan, Milo A.; Behnke, M; Frey, Martin; Grueter, Thomas; Brändli, O; Lichtenschopf, Alfred; Guyatt, Gordon; Schünemann, Holger J.

doi:10.1186/1477-7525-2-1

Cited by 214 publications

(95 citation statements)

References 26 publications

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“…We only considered exacerbations that required out- or inpatient treatment with systemic corticosteroids and/or antibiotics. The secondary outcomes included HRQOL as measured by the self-administered standardized CRQ [12,13] and the Feeling Thermometer [14], dyspnea as measured by the modified Medical Research Council dyspnea scale and mortality. All of these outcomes have been validated in the languages required here (German, French and Italian) and have seen extensive use in clinical research and practice.…”

Section: Methodsmentioning

confidence: 99%

Early versus Late Pulmonary Rehabilitation in Chronic Obstructive Pulmonary Disease Patients with Acute Exacerbations: A Randomized Trial

et al. 2011

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Background: Around the world, the timing of referral of chronic obstructive pulmonary disease (COPD) patients for pulmonary rehabilitation differs from immediately after exacerbation (early) to later on when patients are in a stable state (late). There are no trials comparing the different time points of referral for pulmonary rehabilitation. Objectives: Our aim was to compare the effects of early and late pulmonary rehabilitation on exacerbation rates and health-related quality of life (HRQOL) in COPD patients with exacerbations. Methods: We randomized COPD patients (Global Initiative for Chronic Obstructive Lung Disease stages II–IV) with a recent exacerbation to early (within 2 weeks) or late pulmonary rehabilitation (starting 6 months after randomization and in a stable state). The primary outcome was the exacerbation rate over 18 months, and secondary outcomes included HRQOL and mortality. We used multivariate analyses and an intention-to-treat analysis approach. Results: We randomized 36 patients to pulmonary rehabilitation. On average, patients with early rehabilitation (n = 19) had 2.61 (SD 2.96) exacerbations requiring systemic corticosteroids and/or antibiotics, compared to 2.77 (SD 3.41) in patients with late rehabilitation (adjusted incidence rate ratio 0.83, 95% confidence interval 0.43–1.63; p = 0.60). Over the 18-month period, patients with late rehabilitation experienced more dyspnea (difference on Chronic Respiratory Questionnaire dyspnea domain 0.74 and on the Medical Research Council dyspnea scale 0.37), but neither these differences nor any difference in HRQOL domains reached statistical significance. Conclusions: We did not find any statistically significant differences between early and late pulmonary rehabilitation. However, our trial indicates that early rehabilitation may lead to faster recovery of HRQOL after exacerbations compared to rehabilitation later on when patients are in a stable state.

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Section: Methodsmentioning

confidence: 99%

Early versus Late Pulmonary Rehabilitation in Chronic Obstructive Pulmonary Disease Patients with Acute Exacerbations: A Randomized Trial

et al. 2011

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“…HRQL was assessed with the German version of the standardized, self-administered CRQ [24, 25]. A difference in CRQ scores of 0.5 points was considered to be clinically relevant [26].…”

Section: Methodsmentioning

confidence: 99%

Home-Based Exercise Training as Maintenance after Outpatient Pulmonary Rehabilitation

Moulin

Taube²,

Wegscheider³

et al. 2008

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Background: Pulmonary rehabilitation is successful in improving exercise capacity and quality of life in patients with chronic obstructive pulmonary disease (COPD). However, training effects diminish over time. Objectives:We evaluated the effects of simple, daily, structured, self-monitored, home-based exercise training for patients with moderate COPD after a 3-week outpatient rehabilitation. Methods: We conducted a randomized, controlled, observer-blind trial. Twenty patients were recruited. Ten patients performed home-based exercise training (mean age 67 years, 95% confidence interval [CI] 63–72; FEV₁ 58.6%, 95% CI 53.8–63.4), and 10 patients served as controls (mean age 72 years, 95% CI 69–77; FEV₁ 62.5%, 95% CI 57.7–67.3). At baseline, and after 3 and 6 months, we assessed exercise capacity (6-min walk test, 6MWT, primary endpoint), health-related quality of life (Chronic Respiratory Questionnaire, CRQ) and lung function. An intention-to-treat analysis was performed using two-way ANOVA models for comparison of time trends between random groups. Results: The training group had better results than the control group in 6MWT (p = 0.033), in CRQ total (p = 0.027), CRQ dyspnea (p = 0.014) and CRQ fatigue (p = 0.016). Improvement in FEV₁ was also better in the intervention group than in the control group (p = 0.007). Conclusions: We demonstrated that training effects obtained from an outpatient rehabilitation program can be maintained by home-based exercise training in patients with moderate COPD.

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“…Frequent mental distress (mental health problems experienced on 14 or more of the past 30 days) has been found to be associated with unhealthy and high-risk behaviors such as smoking, alcohol and drug use [20–22, 26, 27]. Mental distress is also associated with medical conditions such as heart disease, asthma, and arthritis, as well as health outcomes such as mortality and hospitalizations.…”

Section: Introductionmentioning

confidence: 99%

Social-Emotional Support, Life Satisfaction, and Mental Health on Reproductive Age Women’s Health Utilization, US, 2009

Willet

Hayes

Zaha

et al. 2012

Matern Child Health J

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To examine the associations among social-emotional support, life satisfaction, and mental health with not having a routine checkup among women of reproductive age in the US, data from the 2009 Behavioral Risk Factor Surveillance System, a population-based telephone survey of health behaviors, were analyzed among reproductive aged (18–44 years) women in the US. Prevalence estimates were calculated for not having a routine checkup in the past year with measures of social-emotional support, life satisfaction, and mental distress. Independent multivariable logistic regressions for each measure assessed not having a routine checkup within the past year with adjustment for age, race/ethnicity, education level, and health care coverage. Among women of reproductive age, 33.7 % (95 % CI 33.0–34.4) did not have a routine checkup within the past year. Factors associated with not having a routine checkup included: having social-emotional support most of the time (AOR = 1.29, 95 % CI 1.20–1.38) or sometimes or less (AOR = 1.47, 95 % CI 1.34–1.61) compared to those who reported always having the social-emotional support they need; reporting life satisfaction as being satisfied (AOR = 1.27, 95 % CI 1.19–1.36) or dissatisfied (AOR = 1.65, 95 % CI 1.43–1.91) compared to being very satisfied; and frequent mental distress (AOR = 1.19, 95 % CI 1.09–1.30) compared to those without. Women who report lower levels of social-emotional support, less life satisfaction, and frequent mental distress are less likely to see a doctor for a routine checkup. Targeted outreach that provides appropriate support are needed so these women can access clinical services to increase exposure to preventive health opportunities and improve overall health.

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Untitled

Cited by 214 publications

References 26 publications

Early versus Late Pulmonary Rehabilitation in Chronic Obstructive Pulmonary Disease Patients with Acute Exacerbations: A Randomized Trial

Early versus Late Pulmonary Rehabilitation in Chronic Obstructive Pulmonary Disease Patients with Acute Exacerbations: A Randomized Trial

Home-Based Exercise Training as Maintenance after Outpatient Pulmonary Rehabilitation

Social-Emotional Support, Life Satisfaction, and Mental Health on Reproductive Age Women’s Health Utilization, US, 2009

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