Xerostomia in geriatric patients: a burgeoning global concern

Anil, Sukumaran; Vellappally, Sajith; Hashem, Mohamed; Preethanath, Reghunathan S.; Patil, Shankargouda; Samaranayake, LP

doi:10.1111/jicd.12120

Cited by 75 publications

(76 citation statements)

References 64 publications

(126 reference statements)

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“…Candida species are commensal microorganisms in the oral cavity in 40-60 % of the population and only cause disease when disturbances in the oral microbial balance occur (Teughels et al 2008 ). Oral candidiasis is therefore often seen in elderly people and is frequently associated with antibiotic treatment, hyposalivation, impaired local or systemic immune system, neglected oral hygiene, dentures and smoking (Anil et al 2014 ;Pires et al 2002 ;Shay et al 1997 ;Torres et al 2002 ). A number of antifungal agents are available for the treatment of oral candidiasis, e.g.…”

Section: Colonisation Of Oral Candida Speciesmentioning

confidence: 99%

Use of Probiotics in Future Prevention and Treatment of Oral Infections

Jørgensen

Keller

2015

Oral Infections and General Health

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The interest for probiotic bacteria to combat biofi lm-related diseases in the oral cavity has arisen during the last decade. The probiotic concept has successfully been used to control gastrointestinal diseases, such as antibiotic-associated diarrhoea and acute infectious diarrhoea. The potential mechanisms of action in the oral cavity are not fully understood, but there are thoughts to be a local effect in the mouth and systemic effect through immune regulation. The purpose of this chapter is to summarise our current knowledge of the potential for probiotics to improve oral and dental health and to discuss its potential in the future prevention of oral diseases. Despite some limitations, the currently available clinical studies appear expectant, and there seem to be evidence of probiotics to improve oral conditions such as dental caries, periodontitis and the colonisation of Candida . However, more long-term clinical studies are needed before evidence-based guidelines can be released.

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Section: Colonisation Of Oral Candida Speciesmentioning

confidence: 99%

Use of Probiotics in Future Prevention and Treatment of Oral Infections

Jørgensen

Keller

2015

Oral Infections and General Health

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“…21 Patients with severe xerostomia will often complain of dry, burning mouth, which can be very painful and interfere with functions. 22 Xerostomia is normally caused by a local factor, radiation therapy. Ionizing radiation causes pronounced changes in salivary glands, and the degeneration of acini.…”

Section: Migratory Glossitismentioning

confidence: 99%

Burning Mouth Syndrome: A Review of the Etiopathologic Factors and Management

Vellappally¹

2016

The Journal of Contemporary Dental Practice

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Burning mouth syndrome (BMS) is characterized by pain in the mouth with or with no inflammatory signs and no specific lesions. Synonyms found in literature include glossodynia, oral dysesthesia, glossopyrosis, glossalgia, stomatopyrosis, and stomatodynia. Burning mouth syndrome generally presents as a triad: Mouth pain, alteration in taste, and altered salivation, in the absence of visible mucosal lesions in the mouth. The syndrome generally manifests spontaneously, and the discomfort is typically of a continuous nature but increases in intensity during evening and at night. The etiopathogenesis seems to be complex and in a large number of patients probably involves interactions among local, systemic, and/or psychogenic factors. The differential diagnosis requires the exclusion of oral mucosal lesions or blood test alterations that can produce burning mouth sensation. Management is always based on the etiological agents involved. If burning persists after local or systemic conditions are treated, then treatment is aimed at controlling neuropathic symptoms. Treatment of BMS is still unsatisfactory, and there is no definitive cure. As a result, a multidisciplinary approach is required to bring the condition under better control. The aim of this review was to discuss several aspects of BMS, update current knowledge, and provide guidelines for patient management.

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“…Among the causes of xerostomia, which do not involve a decrease in salivary secretion, are dehydration, cognitive and neurological disorders, oral sensory dysfunction and oral breathing 59 . There are many causes that can induce hyposalivation, the most common are the adverse effects of pharmacological agents, considered as a iatrogenic consequence, the most prevalent being SS, external beam radiotherapy, and diabetes mellitus (more than half of the patients with dia- betes type I and II have hyposalivation), among others [63][64][65][66][67][68][69] ( , among others [20][21][22][23][24][25][26][27][28] (Table 1).…”

Section: Oral Manifestations Of Sjögren's Syn-dromementioning

confidence: 99%

“…However, despite these common factors, there may be other manifestations that complicate the initial diagnosis [17][18][19][20][21][22][23][24][25][26][27][28][29][30][31][32][33][34][35] (Table 1). …”

Section: Introductionmentioning

confidence: 99%

Dental perspective on Sjögren’s syndrome: literature review

et al. 2015

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Abstract:The human body releases around 500-600mL of saliva daily, however when values of unstimulated whole saliva range from 0.1 to 0.2mL/ min, there is a condition called Hyposalivation or hyposialia. Hyposalia is characterized by a large number of systemic conditions, including Sjögren's syndrome, a chronic autoimmune disease that affects between 0.1 and 3% of the world population and is characterized by exocrinopathy of the salivary glands leading to glandular hypofunction and thus decreasing the normal salivary flow. Saliva is part of innate immunity, when there is a decrease in protein secretion, numerous oral manifestations occur such as dental caries, candidiasis, gingival disease, angular cheilitis, lymphomas of the salivary glands, dysphagia, erythematous and fissured tongue, among others. Currently there is no defined dental treatment, however there are alternative treatments by sialogogues and salivary substitutes, plus non-pharmacological therapies, which seek to maintain the ecology and oral conditions stable, in addition to preventive and restorative dental treatment for lesions already established as a consequence of the disease. The aim of this study is to conduct a literature review on the characteristics, classification, oral manifestations and dental management of Sjögren's syndrome.

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Xerostomia in geriatric patients: a burgeoning global concern

Cited by 75 publications

References 64 publications

Use of Probiotics in Future Prevention and Treatment of Oral Infections

Use of Probiotics in Future Prevention and Treatment of Oral Infections

Burning Mouth Syndrome: A Review of the Etiopathologic Factors and Management

Dental perspective on Sjögren’s syndrome: literature review

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