Xanthones from the Roots of Moutabea guianensis Aubl.

Filho, Haroldo da Silva Ripardo; Pacheco, L. C.; Andrade, Edinaldo da Silva; Corrêa, Marivaldo José Costa; Araújo, Railda Neyva Moreira; Guilhon, Giselle Maria Skelding Pinheiro; Silva, Joyce Kelly R. da; Santos, Lourivaldo S.

doi:10.3390/molecules20010127

Cited by 7 publications

(6 citation statements)

References 16 publications

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“…A more sophisticated error occurred when the numbering schemes of two complete ring systems were intermixed [ 50 ], leading to massive deviations between the experimental and predicted chemical shift values at nearly all positions; in this particular case, another possible assignment error (carbon 1 versus 4a) increased the complexity of the correction, as can be seen in Figure 7 .…”

Section: Resultsmentioning

confidence: 99%

The Advantage of Automatic Peer-Reviewing of 13C-NMR Reference Data Using the CSEARCH-Protocol

Robien¹

2021

Molecules

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A systematic investigation of the experimental 13C-NMR spectra published in Molecules during the period of 1996 to 2015 with respect to their quality using CSEARCH-technology is described. It is shown that the systematic application of the CSEARCH-Robot-Referee during the peer-reviewing process prohibits at least the most trivial assignment errors and wrong structure proposals. In many cases, the correction of the assignments/chemical shift values is possible by manual inspection of the published tables; in certain cases, reprocessing of the original experimental data might help to clarify the situation, showing the urgent need for a public domain repository. A comparison of the significant key numbers derived for Molecules against those of other important journals in the field of natural product chemistry shows a quite similar level of quality for all publishers responsible for the six journals under investigation. From the results of this study, general rules for data handling, data storage, and manuscript preparation can be derived, helping to increase the quality of published NMR-data and making these data available as validated reference material.

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Section: Resultsmentioning

confidence: 99%

The Advantage of Automatic Peer-Reviewing of 13C-NMR Reference Data Using the CSEARCH-Protocol

Robien¹

2021

Molecules

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“…18 For that reason, the Amazon rain forest is one of the main spots on the planet where chemical and biological screening programs are the easiest and cheap ways of identifying plants as a potential source of new medicines. The present work reports the chemical screening of 895 plant extracts aiming the identification of their antioxidant potential, as well as to look for alkaloids, quinones [19][20] and cardenolides derivatives, 21 which are compounds already related to antioxidant activity.…”

Section: Discussionmentioning

confidence: 99%

Analysis of Brazilian Plant Extracts as Potential Source of Antioxidant Natural Products Using Bench-Top Assays

Marin

Cavarsan

Díaz

et al. 2018

FRA

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Introduction:The present work reported the antioxidant and chemical screening of Brazilian plant aqueous and organic extracts. Methods: An amount of 895 Brazilian Amazon aqueous and organic plant extracts were tested in thin layer chromatography plates (TLC) using 2, 2-diphenyl-1-picrylhydrazyl (DPPH), β-carotene, Dragendorff's reagent, Kedde's reagent, and KOH reagent so as to evaluate antioxidant activity and chemical profiles. Antioxidant and DPPH free radical scavenging activities results were submitted to chi-square analyses. Results: Only 8.60% of the extracts showed β-carotene/bleaching response, while 96.09% of the extracts responded as a radical scavenger, alkaloids occurred in 8.0% of the extracts whereas anthraquinones occurred in 0.89% of the extracts and cardenolides in 3.89% of the extracts. Conclusion: Present findings described that Amazon plant extracts have a huge potential to be a source of antioxidant compounds to be used in preventive medicine, as well as the chemical screening revealed that their plants can be strategically assessed as a source of alkaloids to be tested in further biological assays.

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“…As described above, 1,8-dihydroxy-4,6-dimethoxyxanthone (59), 1,8-dihydroxy-4,6,7-trimethoxyxanthone ( 60 ), 1,8-dihydroxy-4,5,6-trimetoxyxanthone ( 61 ), 1,8-dihydroxy-4,5,6,7-tetra-methoxyxanthone ( 62 ), 1-hydroxy-4,5,6,7,8-pentamethoxyxanthone ( 63 ) ( Figure 5 ) [ 162 ]. The DPPH scavenging order was 59 (1.3 μg) < 63 (0.6 μg) < 60 and 61 (0.3 μg) < 62 (0.15 μg).…”

Section: Bioactivities Of Xanthonesmentioning

confidence: 99%

Chemical and Biological Research on Herbal Medicines Rich in Xanthones

Ruan¹,

Zheng²,

Liu³

et al. 2017

Molecules

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Xanthones, as some of the most active components and widely distributed in various herb medicines, have drawn more and more attention in recent years. So far, 168 species of herbal plants belong to 58 genera, 24 families have been reported to contain xanthones. Among them, Calophyllum, Cratoxylum, Cudrania, Garcinia, Gentiana, Hypericum and Swertia genera are plant resources with great development prospect. This paper summarizes the plant resources, bioactivity and the structure-activity relationships (SARs) of xanthones from references published over the last few decades, which may be useful for new drug research and development on xanthones.

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Xanthones from the Roots of Moutabea guianensis Aubl.

Cited by 7 publications

References 16 publications

The Advantage of Automatic Peer-Reviewing of 13C-NMR Reference Data Using the CSEARCH-Protocol

The Advantage of Automatic Peer-Reviewing of 13C-NMR Reference Data Using the CSEARCH-Protocol

Analysis of Brazilian Plant Extracts as Potential Source of Antioxidant Natural Products Using Bench-Top Assays

Chemical and Biological Research on Herbal Medicines Rich in Xanthones

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