Xanthomatosis and the Reticuloendothelial System

Rowland, R

doi:10.1001/archinte.1928.00130220002001

Cited by 164 publications

(8 citation statements)

References 48 publications

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“…Involvement of the spinal dura mater was a feature of this case, the nodules being similar to those seen on the cerebral dura of adults and children by Veit (1922), Griffith (1924), Kyrklund (1926);Herzenberg (1928), Rowland (1928), Chiari (1931), and Cavanagh and Russell (1954). Xanthomatous infiltration of cord substance, as described by Feigin (1956), was not seen.…”

Section: Discussionsupporting

confidence: 81%

Neural and visceral xanthomatosis in adults

Miller

Ramsden

1965

J Clin Pathol

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SYNOPSISThe clinical, pathological, and chemical findings in a fatal case of generalized HandSchiiller-Christian disease in a man of 33 years are presented in case 1. The necropsy examination revealed granulomatous infiltration of the infra-orbital fat, the pituitary stalk, and the posterior lobe of the pituitary and also of the skull bones and the thyroid cartilage. The spinal dura mater contained multiple xanthomatous deposits which had produced degenerative changes in the cord substance by epidural compression. Interesting features were the tumour-like enlargement of the right heart, massive pancreatic and renal infiltration, also heavy constricting xanthomatous mantles which had produced compression of both kidneys and adrenal glands.Case 2 is an example of xanthomatous granuloma, confined to the lungs, in a man of 57 years, and not associated with diabetes insipidus. The histological appearances were those of long-standing chronic xanthoma with marked cystic changes in the lungs, dilated bronchioles, and thick-walled stenosed pulmonary arteries.The pathogenesis of Hand-Schiiller-Christian disease is briefly discussed.

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Section: Discussionsupporting

confidence: 81%

Neural and visceral xanthomatosis in adults

Miller

Ramsden

1965

J Clin Pathol

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“…The occurrence of dystrophia adiposogenitalis has been described in detail by Schiiller (1915), Schiiller and Chiari (1930), and Chester and Kugel (1930. Dwarfism was a feature noted by Rowland (1928) and Snapper and Parisel (1933). Deafness may result from lesions in the petroustemporal bone and mastoid processes.…”

Section: Discussionmentioning

confidence: 87%

“…We will therefore pass on to other theories of the mechanism of Letterer-Siwe disease, particularly those concerned with metabolism and infection. Rowland (1928), after describing the clinical and pathological features suggested that the disease resulted from a primary disturbance of lipoid metabolism. This hypothesis was further strengthened by the work of Epstein and Lorenz (1930), who had studied the chemical nature of the deposits in Gaucher's disease, Niemann-Pick disease, and Hand-Schuller-Christian disease.…”

Section: Discussionmentioning

confidence: 99%

Reticulondothelial Granuloma: A Review with a Report of a Case of Letterer-Siwe Disease

Claireaux¹,

Lewis²

1950

Archives of Disease in Childhood

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“…In the early stage of the disease there may be papillary outgrowths into the bronchioles causing partial obstruction (Rowland, 1928). In a case described by Forsee and Blake (1954) xanthomatous tissue was seen on bronchoscopy to be protruding into the lumen of the left lower lobe bronchus, and Turner, Davidson, and White (1925) showed that this could occur throughout the bronchial tree from the larynx to the smaller bronchi.…”

Section: Discussionmentioning

confidence: 98%

“…Following the work of Rowland (1928) it was included in the group of xanthomatoses along with Gaucher's and Niemann-Pick's disease. However, it is now looked on as a primary reticulo-endotheliosis or histiocytosis in which the histiocytic cells may become secondarily infiltrated with fat (Wallgren, 1940).…”

mentioning

confidence: 99%