Xanthoma of the Thoracic Spine: A Case Report and Review of Literature

Abstract

Xanthoma arising in bone is a very rare occurrence with only a few case reports in literature. Xanthoma arising in the spine is extremely rare with only four cases previously reported. We report a case of xanthoma of the thoracic spine in a 75-year-old male with hyperlipidemia. The imaging appearances and a review of literature will also be provided.

Primary intraosseous xanthogranuloma in adult cervical spine: A case report of benign cause of lytic bone lesion

“…No fixation Jain et al, 2011 [12] 22 years/ female T7 Body, left pedicle +/+ Not mentioned Laminectomy and rectangular loop fixation Agabegi et al, 2011 [13] 47/ female L2 Body, right psoas, retroperitoneum −/− Not mentioned Laminectomy, debulking, and T10-L4 transpedicular fixation Mcloughlin et al, 2019 [14] 75 years/ male both children and adults, this is the second case to be reported in the cervical spine as intraosseous lesion.…”

“…Regarding systemic associations, hyperlipidemia and cutaneous xanthoma were found in 69% and 53% of patients of bone xanthomas, respectively. [ 11 ] Among vertebral xanthomas, only two cases have reported hyperlipidemia, [ 11 14 ] and out of these, only one had documented cutaneous stigmata. [ 11 ] A case closely resembling to ours in the pediatric age group has been documented.…”

“…[ 2 3 4 5 6 7 8 ] Intraosseous involvement is rare, and only six cases have been reported in the adult population. [ 9 10 11 12 13 14 ] Here, we report a case of primary xanthoma occurring in the cervical spine in a 50-year-old male, presenting as lytic expansile lesion which was presumed to be aggressive lesion such as mets, myeloma, or tuberculous granuloma. This is the seventh case among adult spinal intraosseous xanthoma.…”