Xanthogranulomatous Pyelonephritis: Synchronous Upper and Lower Gastrointestinal Bleed

Mirza, Muhammad Usman; Taunay, John Van; Waleed, Muhammad; Vangimalla, Shiva Shankar; Hegde, Sharana; Moustafa, Muhamad Alhaj

doi:10.1177/2324709619842899

Cited by 3 publications

(3 citation statements)

References 15 publications

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“…The presence of a reno-alimentary fistula not only increases the risk of urinary tract infections but also promotes abscess formation due to the interaction between urine and digestive contents, creating an environment suitable for bacterial growth. Abscesses result in significant pain, swelling, and general illness [ 9 , 12 ]. Furthermore, severe cases of reno-alimentary fistulas can lead to life-threatening sepsis, characterized by systemic infection, causing widespread inflammation, organ dysfunction, and potential fatality if untreated [ 13 ].…”

Section: Discussionmentioning

confidence: 99%

Reno-Duodenal Fistula as a Complication of Staghorn Stones and Renal Pelvis Tumor: A Case Presentation

Alnefaie,

Alsolumany,

Aljahdali

et al. 2024

Cureus

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Reno alimentary fistula, a rare illness characterized by improper connection between the kidney and digestive tract, can lead to urinary tract infections, abscesses, and severe sepsis. It can also be caused by various factors such as chronic infections, malignancy, cryoablation, or abdominal surgical procedures. We present a case of a 60-year-old man with bilateral staghorn stones who was diagnosed with reno-duodenal fistula and underwent a right simple nephrectomy and fistula closure. The histopathology revealed a well-differentiated squamous cell carcinoma that originated from the renal pelvis.

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Section: Discussionmentioning

confidence: 99%

Reno-Duodenal Fistula as a Complication of Staghorn Stones and Renal Pelvis Tumor: A Case Presentation

Alnefaie,

Alsolumany,

Aljahdali

et al. 2024

Cureus

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“…Three different types of XGP are described as the majority are diffuse (90%), with segmental and focal together constituting around 13% of cases [3]. It is one of the challenging diseases to diagnose because the presentation is non-specific with variable clinical features, laboratory abnormalities, and radiological findings [4]. Infliximab is a genetically engineered monoclonal antibody targeted to inhibit the proinflammatory cytokine, tumor necrosis factor-alpha (TNF-α) [5].…”

Section: Introductionmentioning

confidence: 99%

Infliximab-Associated Xanthogranulomatous Pyelonephritis: A Rare Complication

Alzanbagi¹,

Alhazmi²,

Alghamdi³

et al. 2022

Cureus

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Xanthogranulomatous pyelonephritis (XGP) is one of the rare diseases characterized by chronic inflammation and destruction of the renal parenchyma, and it is usually associated with renal infection, and nephrolithiasis. Infliximab is an anti-tumor necrosis factor-alpha (anti-TNF-α) monoclonal antibody, which is widely used for treating inflammatory bowel disease, and it is known to increase the risk of rare and opportunistic infections. In this study, we report a case of XGP presenting after the initiation of infliximab treatment. We highlight one of the possible complications associated with immunosuppression due to infliximab. Furthermore, the importance of increasing the awareness among physicians for early recognition of this rare complication.

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“…XGP has two morphologic subtypes, namely, the focal and diffuse forms, which may extend outside the kidney and can be complicated with fistula formation connecting the urinary tract with the proximate organs ( 1 ). The occurrence of fistulas connecting the kidney to the upper and lower gastrointestinal tract, bronchus, diaphragm, psoas muscle, and skin has been reported ( 2 3 ).…”

Section: Introductionmentioning

confidence: 99%

A Case of Xanthogranulomatous Pyelonephritis with Nephropleural Fistula Formation: Role of MRI in Diagnosis and Treatment

이

문

유

et al. 2021

J Korean Soc Radiol

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Xanthogranulomatous pyelonephritis (XGP) is a rare type of chronic bacterial nephritis, which rarely involves the invasion of adjacent organs or the formation of fistulas due to tissue-destructive granulomatous reactions. Although the invasions of various adjacent organs have been reported in several cases of XGP, MRI data on their features are limited. MRI has a better soft-tissue resolution than CT. Thus, it can identify the extent of extrarenal involvement in advanced XGP, and the findings can be used in treatment planning. Herein, we report a rare case of XGP with nephropleural fistula formation diagnosed using CT and MRI.

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Xanthogranulomatous Pyelonephritis: Synchronous Upper and Lower Gastrointestinal Bleed

Cited by 3 publications

References 15 publications

Reno-Duodenal Fistula as a Complication of Staghorn Stones and Renal Pelvis Tumor: A Case Presentation

Reno-Duodenal Fistula as a Complication of Staghorn Stones and Renal Pelvis Tumor: A Case Presentation

Infliximab-Associated Xanthogranulomatous Pyelonephritis: A Rare Complication

A Case of Xanthogranulomatous Pyelonephritis with Nephropleural Fistula Formation: Role of MRI in Diagnosis and Treatment

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