Xanthogranulomatous Pyelonephritis Associated with
Renal Cell Carcinoma

Papadopoulos, I.; Wirth, B.; Wand, Handan

doi:10.1159/000463873

Cited by 33 publications

(10 citation statements)

References 12 publications

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“…Hence, nephrectomy has been the treatment of choice. However, malignancy is rarely associated with XPN [17,18]. Tasi et al reported an adult case with bilateral diffuse XPN with no fever, who was managed with supportive care without renal replacement therapy.…”

Section: Discussionmentioning

confidence: 99%

Xanthogranulomatous pyelonephritis in pediatric patients: Case report and review of literature

Gupta

Araya

Dharnidharka

2010

Journal of Pediatric Urology

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Section: Discussionmentioning

confidence: 99%

Xanthogranulomatous pyelonephritis in pediatric patients: Case report and review of literature

Gupta

Araya

Dharnidharka

2010

Journal of Pediatric Urology

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“…[4] Lipid-laden macrophage (xanthoma cells) present in the final histopathology of the resected specimen is confirmatory of the diagnosis of XPN though these cells can resemble clear cells of renal cell adenocarcinoma. [5] XPN can be confused with other chronic inflammatory.…”

Section: Discussionmentioning

confidence: 99%

Acute leukemia masquerading as xanthogranulomatous pyelonephritis

2017

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An 82-year-old man presented with high-grade fever, left flank pain with dysuria. Urine culture revealed the growth of Escherichia coli. Contrast-enhanced computed tomography features were suggestive of xanthogranulomatous pyelonephritis (XPN) of the left kidney. Serial hemogram studies revealed markedly raised white cell count with the presence of blast cells. On further evaluation by peripheral blood smears and bone marrow biopsy studies, a background disease setting of acute prolymphocytic leukemia was diagnosed. This is a very rare case report of acute leukemia masquerading as a case of XPN, and the optimum treatment protocol is yet to be established in such a scenario.

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“…In some cases which is difficult to distinguish between XGP and RCC the immunohistochemical stain is needed. There have been reported two cases XGP which positive PAS stain for the foamy macrophages [8][9][10]. XGP is a rare case and most of the cases are unilateral, but bilateral disease has also reported.…”

Section: Discussionmentioning

confidence: 99%

Xanthogranulomatous Pyelonephritis

Lintong¹

2015

MOJCR

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Xanthogranulomatous pyelonephritis (XGP) is grouped as chronic pyelonephritis that showed kidney enlargement resembling a neoplasm, therefore, it is called pseudotumor. XGP causes destruction of the kidney, disturbance of renal function, and an invasion of infection of renal parenchyme into perinephric adipose tissues and peritoneum. Preoperatively, it is often suspected as a renal cell carcinoma. XGP is occurred rarely, it accounts only 1% of all kidney infection. It can be seen in all ages, but more frequently in middle age female and elderly. The main cause of XGP is chronic obstruction and infection of Proteus or E. Coli. Microscopically, the characteristic feature is the existence of lipid-laden foamy macrophages. A surgery is the first choice and the prognosis is better in unilateral infection cases. We reported a 30-year-old female with a clinical diagnosis of ovarial cyst. Post-operative tissue was found in cystic form tissue. Microscopical examination showed a pyelonephritis and foci of lipid-laden foamy macrohages. It was concluded as an XGP case. The XGP case in female 30 years old is very rare. In this case, the causes of XGP were chronic obstruction and infection. The destructed kidney showed a cystic form that looked like an obstructive hydronephrosis.

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Xanthogranulomatous Pyelonephritis Associated with Renal Cell Carcinoma

Cited by 33 publications

References 12 publications

Xanthogranulomatous pyelonephritis in pediatric patients: Case report and review of literature

Xanthogranulomatous pyelonephritis in pediatric patients: Case report and review of literature

Acute leukemia masquerading as xanthogranulomatous pyelonephritis

Xanthogranulomatous Pyelonephritis

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