Xanthogranulomatous Pyelonephritis

Saeed, Sheikh M.; Fine, Gerald

doi:10.1093/ajcp/39.6.616

Cited by 42 publications

(12 citation statements)

References 0 publications

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…Occasionally a perinephric abscess may be present. In one of Saeed's cases the involved tissue encircled a portion of the aorta (Saeed and Fine, 1963). This encasing Gerota's panniculitis may be 4 cm.…”

mentioning

confidence: 93%

See 1 more Smart Citation

Xanthogranulomatous Pyelonephritis and Perirenal Xanthogranuloma1

Elliott

Johnson

Balfour

1968

British Journal of Urology

View full text Add to dashboard Cite

mentioning

confidence: 93%

“…Histochemical studies suggest that it is high. Saeed and Fine (1963) showed that the lipid is chiefly neutral fat and cholesterol esters. Phospholipids and cholesterol were sparingly distributed.…”

mentioning

confidence: 99%

Xanthogranulomatous Pyelonephritis and Perirenal Xanthogranuloma1

Elliott

Johnson

Balfour

1968

British Journal of Urology

View full text Add to dashboard Cite

“…The urine cultures may be sterile because of previous antibiotic therapy or spontaneous elimination of infection. Other factors implicated in the pathogenesis of XGP include abnormal lipid metabolism [17], lymphatic obstruction [18], altered immunological competence and intrinsic disturbances of leukocyte function, such as chemotaxis and phagocytosis [19,20], arterial insufficiency [21], venous occlusion and hemorrhage [16], necrosis of pericalyceal fat [22], and malnutrition [23].…”

Section: Discussionmentioning

confidence: 99%

Diffuse xanthogranulomatous pyelonephritis in a child with severe complications

et al. 2004

View full text Add to dashboard Cite

Xanthogranulomatous pyelonephritis is a rare disease in childhood. Because the symptoms and signs are chronic and non-specific, preoperative diagnosis is usually difficult. We report an 8-year-old boy who had an abdominal mass and anemia for more than 6 months. Fever and dyspnea occurred 4 days prior to admission. Ultrasonography revealed an enlarged right kidney with multiple parenchymal hypoechogenic areas, absence of normal parenchymal structures, and perinephric thickening with multiple calcifications. An abdominal computed tomogram demonstrated an irregular, enlarged right kidney with multiple low-density round areas consistent with hydronephrosis and calculi. Diminished excretion of contrast media and a severe perinephric inflammatory reaction were present. Poor right kidney function was demonstrated by Tc99m-diethylenetriamine penta-acetic acid split renal function examination. We diagnosed xanthogranulomatous pyelonephritis preoperatively based on the clinical and radiological features. The child first had drainage of an extrarenal abscess and antibiotic therapy, followed by definitive nephrectomy. The hospital course was complicated with pleural effusion, peritonitis, pelvic abscess, and sepsis. A two-stage nephrectomy requiring less radical resection and decreasing the surgical complications would have been preferable.

show abstract

“…However, this theory is contradicted by almost constant unilateral involvement and the infrequent finding of hyperlipidemia. Arterial insufficiency was proposed by Saeed and Fine because the lesions of XPN are relatively avascular [12]. However, other lesions associated with relative lack of vascularity such as papillary necrosis are not associated with changes of XPN.…”

Section: Discussionmentioning

confidence: 99%