Xanthogranulomatous orchitis: case report of a rare condition

Abstract

Xanthogranulomatous inflammation is rare with an unclear etiology. One explanation for this condition is a chronic

Xanthogranulomatous Orchitis Combined with Contralateral Acute Pyogenic Orchitis: A Rare Case Report

“…A case of yellowish granulomatous orchitis with contralateral acute suppurative orchitis is described here. This is a rare benign testicular disease characterized by necrosis of testicular tissue followed by lipid-filled macrophage infiltration [5][6][7]. he XGO microscopic analysis indicated an accumulation of foamy tissue cells with mixed heterogeneous inflammatory cells, resulting in significant damage and loss of the testicular parenchyma.…”

Xanthogranulomatous epididymo-orchitis: A single-institutional case series and systematic review

“…XGEO is a rare disease process with a description of 38 cases reported in 29 articles in medical literature. [ 1 2 6 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 23 24 25 26 27 28 29 30 31 32 ] The details of demographics and clinical profile of the patients are summarized in Table 1 . Most of these cases have been reported from the Asian continent ( n = 18), followed by Europe ( n = 13), North America ( n = 3), Africa ( n = 2), and 1 case each from South America and Australia.…”

“…The greatest dimension of lesion size varied from 1.5 cm to 10.9 cm (mean: 3.6 cm). One case each was suggested as torsion of testis[ 30 ] and epidermoid cyst. [ 27 ] Suspicion of malignancy was suggested in 21% of cases on USG.…”

Xanthogranulomatous orchitis: a case series

“…Other organs that may be involved include the liver, appendix, urinary bladder, ovaries, prostate, epididymis, spermatic cord, and the testicles. 6 The aetiology of XGO remains obscure and the exact pathogenesis of this condition is controversial. 7,2 Most theories and proposed mechanisms arise from the literature of XGI of the kidneys, a more familiar disease which is well-studied and widely reported.…”

“…USG features characteristically show a heterogenous, hypoechoic mass or mixed echotexture with absent internal vascularity replacing the entire testis. 6,10,11 There may be areas of necrosis and purulent secretions along with thickening of cord or epididymis. These features may suggest an abscess or a neoplasm.…”