Xanthogalenol and 4'-O-Methylxanthohumol Content in Some American Humulus

A chromosome-level assembly of the “Cascade” hop (Humulus lupulus) genome uncovers signatures of molecular evolution and improves time of divergence estimates for the Cannabaceae family

“…lupuloides grows in central and eastern North America (Small, 1978, 1981; Reeves & Richards, 2011; McCoy et al , 2019). The geographical distribution of Humulus varieties is also consistent with the flavonoid dichotomy, defined as the presence or absence of 4′- O -methylchalcones (Stevens et al , 2000; Hummer et al , 2004).…”

“…lupuloides grows in central and eastern North America (Small, 1978(Small, , 1981Reeves & Richards, 2011;McCoy et al, 2019). The geographical distribution of Humulus varieties is also consistent with the flavonoid dichotomy, defined as the presence or absence of 4'-O-methylchalcones (Stevens et al, 2000;Hummer et al, 2004). Wild hops are not used in brewing due to bitterness and unpleasant aroma; however, wild varieties provide a repository of genetic diversity to develop new cultivars with enhanced resistance to abiotic and biotic stresses.…”

Genic SSRs for European and North American hop (Humulus lupulus L.)

“…Two North Central accessions, Nebraska-492 and Missouri-1020-SG1, grouped together close to the Southwestern group because they share a unique allele, 429 at HLC-003A with accessions from the southern limit of distribution. Evidence for introgression between Southwestern and Eastern H. lupulus populations was previously presented by Hummer et al (2005). In their study, samples of H. l. var.…”

Phytochemical Characterization of Wild Hops (Humulus lupulus ssp. lupuloides) Germplasm Resources From the Maritimes Region of Canada

“…In addition to their importance in beer brewing, hops have been used in traditional herbal medicines as a sleep aid, while modern biomedical research has focused on various components in the development of new therapeutic agents (Stevens and Page 2004;Gerhäuser 2005;Zanoli and Zavatti 2008;Van Cleemput et al, 2009;Karabín et al, 2016). Taxonomic classification and delineation of hops at the species and/or subspecies level has undergone continuous debate and revision, with the utilization of molecular phylogenetics (Murakami et al, 2006;Bassil et al, 2008;Townsend and Henning, 2009;Patzak et al, 2010b), physiological/morphological characteristics (Small, 1978;Tembrock et al, 2016), chemotaxonometric (Stevens et al, 2000;Hampton et al, 2002;Hummer et al, 2005;Vašek et al, 2013), and paleobotany findings (MacGinitie, 1953;Manchester, 2001) being implemented. There is a general consensus that North American and European hop…”

“…Progeny from these crosses include famous named cultivars such as "Brewer's Gold" and "Northern Brewer", themselves strongly contributing to the pedigrees of the majority of today's most commercially important American hops cultivars. While lupuloides genetic resources from the Great Plains regions of North America (Saskatchewan, Manitoba, Montana, North Dakota) have continued to be evaluated for potential use in hops breeding and cultivar development (Stevens et al, 2000;Hampton et al, 2001;Hampton et al, 2002;Hummer et al, 2005;Bassil et al, 2008), to our knowledge, the diversity and characteristics of eastern lupuloides germplasm resources are completely unknown.…”