Xác định hàm lượng acid perflorooctan sulfonic trong mẫu nước bằng phương pháp sắc ký lỏng khối phổ

Abstract

This study used liquid - liquid extraction (LLE) and liquid chromatography Triple Quadrupole Tandem Mass Spectrometry (LC/MS/MS) Agilent 6430 Triple Quad to survey and assessment PFOS contamination in water. The optimistical conditions are: Product ion is m/z = 80 for quantification and m/z = 98.9 to qualifier; collision energy (CE) is 80V, mobile phase is 80% methanol and 20% amonium acetate 5mM. Base on these conditions, PFOS in 1.0 L water is determined by LLE three times with 100 ml DCM. This process has LOD = 0.2 ng/L; LOQ = 1 ng/L; RSD < 21% and recovery > 80%. The results are suitable to requirements of AOAC to analyse PFOS in water samples.