X-ray spectrometry imaging and chemical speciation assisting to understand the toxic effects of copper oxide nanoparticles on zebrafish (
            <i>Danio rerio</i>
            )

Developmental effects of a binary mixture of nanoparticles (NPs) composed of Titanium dioxide (TiO2) and iron oxide (Fe2O3) were identified in Daphnia magna using a chronic toxicity test. Survival, growth, reproduction, and age at first brood were measured throughout 21 days of exposure. Results from this study demonstrated that mixture exposure to NPs (TiO2 and Fe2O3) significantly affects the development of D. magna to maturation and disturbs the reproductive performance in a dose-dependent manner and beginning from the lower dose. Mortality recorded in control group (1 ± 0.365) was significantly lower than in experimental groups (6.94 ± 0.193, 7.19 ± 0.188, 7.62 ± 0.125, 7.62 ± 0.155 individual, in C1, C2, C3, and C4, respectively). Moreover, swimming performances (F4, 35 = 112.9, df = 4, p<0.0001) and heart rate (F4, 25 = 19.37, df = 4, p<0.0001) were also affected. In conclusion, the interaction of binary mixtures can exacerbate toxicological effects that have significant implications for appropriately assessing the ecotoxicological effects of emerging pollutants. Further investigation and the results reported in the present study will be useful in environmental policies.

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X-ray spectrometry imaging and chemical speciation assisting to understand the toxic effects of copper oxide nanoparticles on zebrafish ( Danio rerio )

Cited by 2 publications

References 59 publications

Copper redox state in cells and aquatic organisms: Implication for toxicity

Copper redox state in cells and aquatic organisms: Implication for toxicity

Developmental effects on Daphnia magna induced by titanium dioxide and iron oxide mixtures

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