X-Linked CNV in Pathogenetics of Intellectual Disability

Genome-wide CNV analysis uncovers novel pathogenic regions in cohort of five multiplex families with neurodevelopmental disorders

“…ZNF711 gene is one of the zinc-finger genes on X chromosome that shows expression of X-linked intellectual disability [ 40 ]. X-linked microdeletions and duplications are reported in various NDDs studies and reviews which in strong agreement with our genetic findings [ 41 ].…”

Combined extended reality and reinforcement learning to promote healthcare and reduce social anxiety in fragile X syndrome: a new assessment tool and a rehabilitative strategy

“…Anxiety disorders are commonly recognized, with an approximate prevalence of 12 months in 18% of the general population. Children, adolescents, and adults with ID are at least four times more likely to meet the criteria for anxiety than those without ID (Tolmacheva et al, 2022 ). People with genetic diseases face a higher risk (Kat et al, 2022 ).…”