Wyniki profilaktycznej terapii radiojodem u chorych w stanie eutyreozy z nadczynnością tarczycy w wywiadzie przed podaniem amiodaronu z utrwalonym migotaniem przedsionków — badanie wstępne

Czarnywojtek, Agata; Zgorzalewicz-Stachowiak, Małgorzata; Woliński, Kosma; Płazińska, Maria Teresa; Miechowicz, Izabela; Kwiecińska, Barbara; Czepczyński, Rafał; Królicki, Leszek; Ruchała, Marek

doi:10.5603/ep.2014.0036

Cited by 3 publications

(2 citation statements)

References 39 publications

(44 reference statements)

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“…Of note 5 patients required an additional dose of radioactive iodine during this study. 45 In another study performed by Kunii et al, the efficacy of Bepridil was tested in converting patients with atrial fibrillation to sinus rhythm in those with and without co-morbid hyperthyroidism. The authors found that Bepidril was equally efficacious irrespective of thyroid status.…”

Section: Pathophysiologymentioning

confidence: 99%

Atrial fibrillation and hyperthyroidism: A literature review

Reddy

Taha

Kundumadam

et al. 2017

Indian Heart Journal

100

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Atrial fibrillation is the most common arrhythmia worldwide with increasing frequency noted with age. Hyperthyroidism is a well-known cause of atrial fibrillation with a 16%–60% prevalence of atrial fibrillation in patients with known hyperthyroidism Ross et al. (2016). While hyperthyroidism as a causative factor of atrial fibrillation is well established, this literature review aims to answer several questions on this topic including:1. The relationship of atrial fibrillation to hyperthyroidism2. Atrial fibrillation as a predictor of hyperthyroidism3. The pathophysiology of thyrotoxic atrial fibrillation4. Subclinical hyperthyroidism and the relationship with atrial fibrillation5. Cardioversion and Catheter ablation of hyperthyroid patients with atrial fibrillation6. Thrombotic risk of hyperthyroid patients with atrial fibrillation7. Management of Thyrotoxic Atrial fibrillation8. Pharmacological rhythm control in patients with hyperthyroidism and atrial fibrillation9. Treatment of Hyperthyroidism to prevent atrial fibrillation10. Clinical Implications of Hyperthyroidism and Atrial Fibrillation

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Section: Pathophysiologymentioning

confidence: 99%

Atrial fibrillation and hyperthyroidism: A literature review

Reddy

Taha

Kundumadam

et al. 2017

Indian Heart Journal

100

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“… 22 The prevention or treatment of AIT by RIT, despite low RAIU, appears to be safe and effective, especially in patients who require a steady administration of AM. 40 Hence, we have undertaken to apply a preventive dose of RIT as the treatment of choice for AIT. In the future, it would be interesting to evaluate the quality of life in this very small focus group of patients.…”

Section: Discussionmentioning

confidence: 99%

Dysfunction of the thyroid gland during amiodarone therapy: a study of 297 cases

Czarnywojtek

Płazińska

Zgorzalewicz-Stachowiak³

et al. 2016

TCRM

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AimThis study aims to explore and compare the efficacy of radioiodine treatment (RIT) in hyperthyroid and euthyroid patients who have been treated with amiodarone (AM) in the past or are currently undergoing AM treatment. Clinical observation of a group of patients with amiodarone-induced hypothyroidism during a 12-month follow-up period was used for comparison.DesignThis was a observational, two-centered study. Patients were assessed at baseline and at 2 months, 6 months, 8 months, and 12 months after RIT.PatientsGroup A: At baseline (61 males [M] and 17 females [F], mean age 50±19 years), there were 78 euthyroid patients with cardiac arrhythmias, who were treated with AM and developed amiodarone-induced thyrotoxicosis, and currently require retreatment with AM. Group B: Hyperthyroid patients (92 M and 26 F, mean age 72±11.8 years) after AM therapy in the past. Group C: Hyperthyroid patients (66 M and 13 F, mean age 63.9±13.2 years) currently treated by AM. Group D: Hypothyroid patients (6 M and 16 F, mean age 61.4±10.4 years) after AM therapy. The patients from Groups A, B, and C were retreated with AM after ~3–6 weeks of RIT.ResultsIn Group A, after 12 months of RIT therapy, recurrent thyrotoxicosis was observed in six (7.7%) cases, and persistent hypothyroidism was diagnosed in 42 (53.8%) cases. In Group B, hyperthyroidism occurring during treatment with AM was found in 40 (33.9%) patients, and permanent hypothyroidism was observed in eleven (12.5%) cases. After annual follow-up in Group C, nine (11.4%) patients were diagnosed with hypothyroidism, while 27 (34.1%) patients were diagnosed with hyperthyroidism. In Group D, all patients had permanent hypothyroidism and when the concentration of serum thyroid-stimulating hormone was >10 µIU/mL, l-thyroxine was applied.ConclusionOur study showed that radioiodine administration is advisable in certain circumstances, even in euthyroid patients. It allows for continuation of further long-term AM treatment. Additionally, RIT allows for the reintroduction of AM therapy that was previously terminated. Hence, it can help control life-threatening tachyarrhythmias and decrease episodes of thyrotoxicosis.

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Heart Follows Thyroid

Potempa¹,

Jonczyk²

2015

Biol Med (Aligarh)

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Wyniki profilaktycznej terapii radiojodem u chorych w stanie eutyreozy z nadczynnością tarczycy w wywiadzie przed podaniem amiodaronu z utrwalonym migotaniem przedsionków — badanie wstępne

Cited by 3 publications

References 39 publications

Atrial fibrillation and hyperthyroidism: A literature review

Atrial fibrillation and hyperthyroidism: A literature review

Dysfunction of the thyroid gland during amiodarone therapy: a study of 297 cases

Heart Follows Thyroid

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