WRKY transcription factors: from DNA binding towards biological function

Ülker, Bekir; Somssich, Imre E.

doi:10.1016/j.pbi.2004.07.012

Cited by 841 publications

(660 citation statements)

References 51 publications

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“…Among the induced genes, 1 encodes a WRKY transcription factor (OsAM205). WRKY transcription factors are an ancient type of eukaryotic transcription factors comprising a large multigene family in plants but are absent from yeast and animals (69). Individual members play a role in plant development and defense against pathogen attack (69).…”

Section: Discussionmentioning

confidence: 99%

Comparative transcriptomics of rice reveals an ancient pattern of response to microbial colonization

Güimil

Chang

Zhu

et al. 2005

Proc. Natl. Acad. Sci. U.S.A.

332

270

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Glomalean fungi induce and colonize symbiotic tissue called arbuscular mycorrhiza on the roots of most land plants. Other fungi also colonize plants but cause disease not symbiosis. Wholetranscriptome analysis using a custom-designed Affymetrix GeneChip and confirmation with real-time RT-PCR revealed 224 genes affected during arbuscular mycorrhizal symbiosis. We compared these transcription profiles with those from rice roots that were colonized by pathogens (Magnaporthe grisea and Fusarium moniliforme). Over 40% of genes showed differential regulation caused by both the symbiotic and at least one of the pathogenic interactions. A set of genes was similarly expressed in all three associations, revealing a conserved response to fungal colonization. The responses that were shared between pathogen and symbiont infection may play a role in compatibility. Likewise, the responses that are different may cause disease. Some of the genes that respond to mycorrhizal colonization may be involved in the uptake of phosphate. Indeed, phosphate addition mimicked the effect of mycorrhiza on 8% of the tested genes. We found that 34% of the mycorrhiza-associated rice genes were also associated with mycorrhiza in dicots, revealing a conserved pattern of response between the two angiosperm classes.expression profiling ͉ Glomus ͉ Oryza sativa ͉ pathogenesis ͉ phosphate

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Section: Discussionmentioning

confidence: 99%

Comparative transcriptomics of rice reveals an ancient pattern of response to microbial colonization

Güimil

Chang

Zhu

et al. 2005

Proc. Natl. Acad. Sci. U.S.A.

332

270

View full text Add to dashboard Cite

show abstract

“…Although little is known about this transcription factor family, their members seem to be upregulated by wounding, pathogen infection and diverse abiotic stresses, such as cold or drought (see reviews in Eulgem et al, 2000;Ü lker and Somssich, 2004). Interestingly, the WRKY transcription factor family is involved in defense-induced mitogenactivated protein kinase signaling cascades (Asai et al, 2002) and in leaf senescence (Robatzek and Somssich, 2002) (albeit only marginally in the Cuthbert trial) was sod-chl, a Cu/Zn superoxide dismutase gene.…”

Section: Discussionmentioning

confidence: 99%

Association genetics in Pinus taeda L. II. Carbon isotope discrimination

et al. 2008

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Dissection of complex traits that influence fitness is not only a central topic in evolutionary research but can also assist breeding practices for economically important plant species, such as loblolly pine (Pinus taeda L). In this study, 46 single nucleotide polymorphisms (SNPs) from 41 disease and abiotic stress-inducible genes were tested for their genetic association with carbon isotope discrimination (CID), a timeintegrated trait measure of stomatal conductance. A familybased approach to detect genotype/phenotype genetic association was developed for the first time in plants by applying the quantitative transmission disequilibrium test on an association population of 961 clones from 61 families (adopted from previous breeding programs) evaluated for phenotypic expression of CID at two sites. Two particularly promising candidates for their genetic effects on CID are: dhn-1, involved in stabilization of cell structures, and lp5-like, a glycine rich protein putatively related to cell wall reinforcement proteins, both of which were shown in previous studies to be water-deficit inducible. Moreover, association in lp5-like involves a nonsynonymous mutation in linkage disequilibrium with two other nonsynonymous polymorphisms that could, by acting together, enhance overall phenotypic effects. This study highlights the complexity of dissecting CID traits and provides insights for designing second-generation association studies based on candidate gene approaches in forest trees.

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“…WRKY factors were generally regarded as being plant specific, but their identification in the protist Giardia lamblia and the slime mold Dictyostelium discoideum imply an earlier origin (Ü lker and Somssich, 2004;Pan et al, 2009). They may have evolutionary links with transposons such as Mutator-like elements and could have originated from a BED finger intermediate (an atypical zinc finger DNA-binding domain found both in cellular chromatin boundary element-binding proteins BEAF and DREF and in transposases from animals), although this is controversially debated (Babu et al, 2006;Yamasaki et al, 2008).…”

Section: The Wrky Factorsmentioning

confidence: 99%