Wrist actigraphy for measuring sleep in intervention studies with Alzheimer's disease patients: Application, usefulness, and challenges

Levels of physical activity and sleep patterns among older people with dementia living in long-term care facilities: A 24-h snapshot

“…This rate is higher than that reported in previous studies conducted with people with dementia, whereby non-adherence rates of approximately one-third were observed [30]. The inclusion of a large sample -415 residents from 28 long-term care facilities and with varying levels of cognitive impairment -may have contributed to the higher rate of non-adherence we observed.…”

Glucose-6-phosphate dehydrogenase deficiency and Alzheimer’s disease: Partners in crime? The hypothesis

“…G6PD deficiency is a triggering factor in oxidative stress mechanism which in turn, exacerbates the consequent lipid peroxidation [45]. Researchers have been trying to identify factors that increase the risk of AD such as aerobic exercise, pesticides, elevated serum cholesterol concentrations, carotenoids, abdominal obesity, and exposure to aluminum, head injury, malnutrition, immune system dysfunctions, and infectious agents [46][47][48][49][50][51]. G6PD deficiency is the most common genetic defect and enzymopathy worldwide, affecting approximately 400 million people and causing acute hemolysis in patients exposed to oxidative compounds such as menthol, naphthalene, antimalarial drugs, and fava beans [52].…”

High frequency of getting out of bed in patients with Alzheimer's disease monitored by non‐wearable actigraphy

“…However, measuring sleep patterns in these patients remains challenging. The questionnaires used to evaluate sleep in patients with dementia have low validity because of patient memory loss . Consequently, caregivers are often asked to evaluate sleep in patients with dementia using questionnaires or sleep diaries.…”

“…Consequently, caregivers are often asked to evaluate sleep in patients with dementia using questionnaires or sleep diaries. Unfortunately, studies have shown that the validity of caregiver observation of nocturnal behavior in patients with dementia is also low compared with objective measurements . Sleep monitoring instruments, such as polysomnography and wearable actigraphy, are regarded as the gold standard for sleep measurement.…”

“…Sleep monitoring instruments, such as polysomnography and wearable actigraphy, are regarded as the gold standard for sleep measurement. However, patients with moderate‐to‐severe dementia rarely cooperate in wearing these types of equipment . The goal of the current study was to quantitatively describe the sleep of patients with AD and to identify any patterns of sleep disturbance.…”