Wound Healing Effect of King Alferd’s Mushroom (Daldinia Concentrica) Used by Tribes of Sirumalai Hills, Tamilnadu, India

Abstract

Objective: The present investigation is an attempt to an ethnomycological mushroom survey carried out among the paliyar tribals of five settlements in Sirumalai hills. Daldinia concentrica, mushroom reported by the tribals for the wound healing activity was evaluated in vivo in rat model. Methods:The indigenous information of the tribal people was collected through personal interviews during field trips and also the ethno reported mushroom Daldinia concetrica was analysed for its phytochemical constituents by Harborne method and its potential wound healing activity in Albino Wistar rats by excision wound model. Results:The exploration revealed that 92% of the respondents consume mushroom as food and four mushrooms are used in ethnomedicine in the study area namely, Daldinia concentrica, Calvatia gigantean, Termitomyces microcarpus and Podaxis pistillaris. Daldinia concentrica for wound healing, is the first ethnomycological report, thus the further study on Daldinia revealed that the mushroom sample consists of alkaloid 0.97±0.07 mg/kg, flavanoid 2.97±0.12 mg/kg, phenol 0.32±0.01 mg/kg, tannin 0.17±0.02 mg/kg, terpenoid 0.07±0.01 mg/kg and saponin 0.09±0.02 mg/kg; and it's in vivo wound healing activity was found to be outstanding around 75-87% compared to that of the commercial ointment neosporin. Conclusion:We believe that wound healing activity of Daldinia mushroom was due to the synergestic effect of phytochemicals present in them. Our results throw in the insight of the traditional use of mushrooms in various treatments.

Mushrooms-Rich Preparations on Wound Healing: From Nutritional to Medicinal Attributes

“…Used for curing stomach upset and to cure stomach pains in woman during menstruation. (Thangaraj et al, 2017) Crinipellis schevczenkovi…”

“…Increased wound healing activity in albino Wistar rats by excision wound model (Thangaraj et al, 2017) Fomes fomentarius Polyporaceae Unspecified Ash combined with oil on skin ailments exerted wound healing promotion (Malik et al, 2017)…”

“…Mushrooms have been eaten for many years due to their flavor, economic and ecological benefits, and therapeutic properties. With the research advances, numerous bioactive compounds obtained from mushrooms have been looked as responsible for their biological and therapeutic properties, with their anti-atherogenic, (Thimal and Kluthe, 1998) Podaxis pistillaris Agaricaceae Unspecified Mushrooms consumption enhanced wound healing (Thangaraj et al, 2017) Sparassis crispa…”

“…Fresh extract powder/paste of fruiting bodies Increases wound healing (Aryal and Budhathoki, 2015) Unspecified Crude extract enhanced wound healing (Chandrawati and Narendra Kumar, 2014) Unspecified Mushrooms consumption enhanced wound healing (Thangaraj et al, 2017) Tremella fuciformis…”

Evaluation of Antibacterial Potential of Daldinia concentrica from North Eastern Region of India

“…The fungus is used in traditional medicine in Yorubaland, South Western Nigeria in the treatment of Pneumonia and other bacterial infections [1][2][3] . It is also used traditionally for curing skin irritation and wound healing 4 . The genus Daldinia contains a variety of compounds which contributes to biological activities.…”