2022
DOI: 10.1016/j.jep.2022.115009
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Wound healing, anti-inflammatory and anti-melanogenic activities of ursane-type triterpenes from Semialarium mexicanum (Miers) Mennega

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Cited by 6 publications
(4 citation statements)
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“…The wound healing potential in present study was evaluated on basis of anti-oxidants, pro-inflammatory cytokines, connective tissue markers and growth markers which are considered as hallmarks for evaluation of wound healing properties of test extracts and we attempted to highlight those markers in present study which showed significant role in wound healing process as can be appreciated from correlation studies ( Fig. 7 ) [ 1 , 2 , 6 , 7 , 23 ].
Fig.
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Section: Resultsmentioning
confidence: 99%
See 1 more Smart Citation
“…The wound healing potential in present study was evaluated on basis of anti-oxidants, pro-inflammatory cytokines, connective tissue markers and growth markers which are considered as hallmarks for evaluation of wound healing properties of test extracts and we attempted to highlight those markers in present study which showed significant role in wound healing process as can be appreciated from correlation studies ( Fig. 7 ) [ 1 , 2 , 6 , 7 , 23 ].
Fig.
…”
Section: Resultsmentioning
confidence: 99%
“…Numerous studies, encompassing both clinical and experimental investigations, have highlighted the role of oxidative stress and pro-inflammatory/inflammatory mediators in delayed wound healing in diabetes [ 23 ]. Although, there are few plant-based preparations ( Centella asiatica ) and mica based (Muscovitum) used for chronic wound healing, researchers have reported accelerated wound healing potential of these preparations [ 24 , 25 ].…”
Section: Introductionmentioning
confidence: 99%
“…The inflammation process also involves different cell types and mediators that may regulate cell chemotaxis, migration, and proliferation in a coordinated manner. An imbalance between tissue homeostasis and inflammatory cytokines may have a negative impact on patient health and has been associated with different diseases such as rheumatoid arthritis, inflammatory bowel disease, Crohn's disease, metabolic disorders, and Alzheimer's disease [8][9][10][11][12][13].…”
Section: Introductionmentioning
confidence: 99%
“…The bark of the stems and roots of the Hippocratea excelsa (HE) plant, commonly known in the central part of Mexico as "cancerina" has been used to treat various diseases (gastric ulcers, kidney diseases, skin conditions, uterine infections, as an anti-inflammatory, as a healing agent, and for the treatment of dysentery) (Alanís et al, 2005;Apaza Ticona et al, 2022;Escobedo Hinojosa et al, 2014;Mena-Rejón et al, 2007;Navarrete et al, 2002;Velázquez et al, 2006). This plant contains active compounds such as tingenone, celastrol, galactitol, pristimerin, excelsine, friedelin, canophyllol, canophyllal, canophyllic acid, triterpenes, sesquiterpene evoninoate and pyridine alkaloids (Cáceres-Castillo et al, 2008;Calzada & Mata, 1995;Furukawa et al, 2002Furukawa et al, , 2018Mata et al, 1990;Mena-Rejón et al, 2007;Navarrete et al, 2002;Perez et al, 1995;Reyes-Chilpa et al, 2003).…”
Section: Introductionmentioning
confidence: 99%