2005
DOI: 10.1111/j.1067-1927.2005.1304s1.x
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Wound healing and TIME; new concepts and scientific applications

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Cited by 129 publications
(90 citation statements)
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References 66 publications
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“…11 An additional method of MMP control could involve the adjustment of the wound pH. 5,12 In addition to affecting enzymatic activity, pH influences oxygen availability. For example, a lowering of pH by just 0.6 units is reported to enhance the release of almost 50% more oxygen into a wound.…”
Section: Introductionmentioning
confidence: 99%
“…11 An additional method of MMP control could involve the adjustment of the wound pH. 5,12 In addition to affecting enzymatic activity, pH influences oxygen availability. For example, a lowering of pH by just 0.6 units is reported to enhance the release of almost 50% more oxygen into a wound.…”
Section: Introductionmentioning
confidence: 99%
“…Ceftriaxone, continued after procedure depending on patient's general condition and local wound. (b) Accurate surgical debridement of crushed or non-viable tissue until reaching a viable and aseptic bed, basing on TIME scheme [20,21]. (c) Dermal substitute application, performed after wound's bed cleaning for several minutes (not more than 5) with saline solution and preparation of the device while preserving 1 mm of margin on each side.…”
Section: Devicesmentioning
confidence: 99%
“…An aspect of wound healing can therefore be assessed by measuring the rate of recovery of the skin barrier function using TEWL measurements. It is therefore not surprised that research studies have used the technique extensively when assessing wound healing treatments (Nakamizo et al , 2013) and is being advocated as part of assessment tools in wound and scar management (Brusselaers, Pirayesh, 2010, Schultz et al, 2005.…”
Section: Clinical Application In Wound Healingmentioning
confidence: 99%