Wound Dressing Based on Banana Peels Waste and Chitosan by Strengthening Lignin as Wound Healing Medicine

Rihayat, Teuku; Suryani, Suryani; Siregar, J. P.; Zaimahwati,; Salmyah,; Helmi, .; Sariadi,; Fitria, Fitria; Satriananda,; Putra, Alfian Pramudita; Fona, Zahra; Juanda, Juanda; Raudah,; Mawaddah,; Nurhanifa,; Riskina, Shafira; Syahputra, Wildan; Jaafar, Jamiluddin

doi:10.1088/1757-899x/506/1/012056

Cited by 14 publications

(2 citation statements)

References 24 publications

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“…In fact, the peel of the green fruit has antimicrobial activity and antioxidant power [ 4 , 5 ]. These healing properties are associated with the presence of minerals like calcium, potassium, magnesium and sodium, as well as phenolic compounds, especially flavonoids and tannins, being present in greater quantity in the green fruit [ 6 , 7 , 8 ]. Flavonoids are one of the most important phenolic groups and are formed by benzene and pyran rings.…”

Section: Introductionmentioning

confidence: 99%

Synthesis and Characterization of Natural Polymeric Membranes Composed of Chitosan, Green Banana Peel Extract and Andiroba Oil

et al. 2022

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Chitosan comprises polymeric macromolecules with technical and biological properties that have been used in biomedical healing applications requiring anti-microbial and anti-inflammatory capacities worldwide. In the tropical regions, green banana peel extract and andiroba oil are considered natural products with wound healing properties. The present study, for the first time, synthesized chitosan/green banana peel extract/andiroba oil (CGA) membranes and analyzed them using scanning electron microscopy (SEM) and the swelling and moisture tests. The CGA membranes together with control membranes of plain chitosan and chitosan plus green banana peel extract, were characterized by contact angle measurement, X-ray diffraction (XRD) and differential scanning calorimetry (DSC). Macroscopic analysis showed significant differences in color and transparency caused by the number of decoction days used for extract preparation and the oil content. SEM observations disclosed the formation of two phases, lipid and polymer, in the CGA. The number of decoction days and the andiroba oil content were inversely related to the swelling moisture uptake. All membranes were found to be hydrophilic with contact angles less than 90°. The incorporation of plant extract and oil promoted the appearance of related XRD peaks. DSC curves revealed a reduction in the enthalpy of the CGA membranes compared with plain chitosan, which might be attributed to the evaporation of the natural extract and oil. Based on these findings, the studied newly synthesized membranes demonstrated a potential for healing epithelial lesions.

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Section: Introductionmentioning

confidence: 99%

Synthesis and Characterization of Natural Polymeric Membranes Composed of Chitosan, Green Banana Peel Extract and Andiroba Oil

et al. 2022

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“…Te layers were incubated at 37 °C for 18-24 hours. Te zone of inhibition on the growth of Escherichia coli and Staphylococcus aureus bacteria can be seen by the presence or absence of a clear area formed around the sample [19].…”

Section: Swelling Testmentioning

confidence: 99%

Synthesis and Characterization of Hydrogel-Based Hyaluronic Acid-Chitosan-Allium sativum Extract for Intraperitoneal Antiadhesion Application

Widiyanti

Priskawati

2023

International Journal of Biomaterials

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Peritoneal Adhesion is a severe case that frequently occurs in patients after laparotomy surgery. Adhesions are pathological attachment that usually appears between the omentum, intestine, and abdominal wall. Several barriers are made to prevent adhesions, including liquid barriers such as sodium hyaluronate and carboxymethyl cellulose (CMC) but are fast absorbed-time hydrogel. The solid barrier has weakness of difficulty in covering all parts of the wound surface. The study aims to synthesize degradable hydrogel from N,O-Carboxymethyl Chitosan (NOCC), Aldehyde-Hyaluronic Acid, and the addition of Allium sativum (garlic oil). The best sample with the concentration of A-HA/NOCC 30 : 10 g/ml was obtained. The composite hydrogel of NOCC/AHA/Allium sativum has susceptible antimicrobial properties. In vitro cytotoxicity assay showed that hydrogel is nontoxic. The degradation time is for two weeks. The in vivo evaluation in a mouse model with an abrasion defect side was done to identify the effectiveness of the NOCC/AHA/A. sativum as antiperitoneal adhesion. Seven days after surgery, the observation of adhesion was performed. Based on all assay results, it can be resumed that the NOCC/AHA/A. sativum hydrogel possibly acts as an innovation to prevent postoperative intraperitoneal adhesion.

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Lignin Composites for Biomedical Applications: Status, Challenges and Perspectives

Terzioğlu

Parın

Sıcak

2020

Lignin

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Wound Dressing Based on Banana Peels Waste and Chitosan by Strengthening Lignin as Wound Healing Medicine

Cited by 14 publications

References 24 publications

Synthesis and Characterization of Natural Polymeric Membranes Composed of Chitosan, Green Banana Peel Extract and Andiroba Oil

Synthesis and Characterization of Natural Polymeric Membranes Composed of Chitosan, Green Banana Peel Extract and Andiroba Oil

Synthesis and Characterization of Hydrogel-Based Hyaluronic Acid-Chitosan-Allium sativum Extract for Intraperitoneal Antiadhesion Application

Lignin Composites for Biomedical Applications: Status, Challenges and Perspectives

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