Wound botulism

Burningham, Mark D; Walter, Frank G.; Mechem, C. Crawford; Haber, Judy; Ekins, Brent R.

doi:10.1016/s0196-0644(94)70253-5

Cited by 34 publications

(14 citation statements)

References 16 publications

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…Seven immunologically distinct toxins have been identified. 13,47,85 Most human cases are caused by types A, B, or E. Type E botulism is usually associated with the ingestion of contaminated seafood. Fatalities have been reported with all three types.…”

Section: Classic Botulism (Foodborne Botulism)mentioning

confidence: 99%

“…For the 47-year period since the first reported case in 1943, there have been only 47 cases of wound botulism reported to the CDC and in the literature. 13,22,61,98 Its rarity was attributed to the failure of the clostridial spores to germinate readily in tissues. It occurred almost exclusively in patients with traumatic and surgical wounds.…”

Section: Wound Botulismmentioning

confidence: 99%

“…Small abscesses at injection sites in a drug abuser may harbor Clostridium botulinum bacteria. 13,36,60,61,64 Sinusitis secondary to cocaine abuse also can be the source of Clostridium botulinum. 60 The organism has been cultured from the abscesses of IV heroin users, and from sinus aspirate of a patient who developed botulism following intranasal cocaine abuse.…”

Section: Wound Botulismmentioning

confidence: 99%

See 2 more Smart Citations

Clinical spectrum of botulism

1998

View full text Add to dashboard Cite

Section: Classic Botulism (Foodborne Botulism)mentioning

confidence: 99%

Section: Wound Botulismmentioning

confidence: 99%

Section: Wound Botulismmentioning

confidence: 99%

See 1 more Smart Citation

Clinical spectrum of botulism

1998

View full text Add to dashboard Cite

“…Supportive therapy includes ventilation for respiratory muscle weakness [15,16] and management of autonomic dysfunction. Current recommendations for botulinum antitoxin treatment is for one 10-ml vial (containing 7500 IU Type A, 5500 IU Type B and 8500 IU Type E equine antitoxin) to be given intravenously [2].…”

Section: Discussionmentioning

confidence: 99%

Wound botulism in drug addicts in the United Kingdom

Mulleague¹,

Bonner²,

Samuel³

et al. 2001

Anaesthesia

View full text Add to dashboard Cite

Clostridium novyi has recently been identified as the causative organism responsible for the deaths of 35 heroin addicts who had injected themselves intramuscularly. We present two heroin addicts who developed C. botulinum infection following intramuscular or subcutaneous injection of heroin. Like C. novyi, this grows under anaerobic conditions and clinical presentation may be similar; however, descending motor or autonomic signs are invariably present in botulism. The prognosis is good if the diagnosis is made early and appropriate treatment commenced.

show abstract

“…Botulinum antitoxin should be administered as soon as ACADEMIC EMERGENCY MEDICINE AUG 1997 VOL 4/NO 8 it is available, and should not await neurophysiologic testing or laboratory confirmation of the diagnosis.' Although the efficacy of antitoxin in wound botulism has not been studied, its benefits in food-borne botulism are widely accepted.'…”

Section: Treatmentmentioning

confidence: 99%

Wound Botulism Associated with Black Tar Heroin

Anderson

Sharma

Feeney

1997

Academic Emergency Medicine

View full text Add to dashboard Cite

Letters of Recommendation vs Questionnaires, Schaider et al. 805predict actual resident performance. Given this preliminary information, we believe that the PPQ may substitute for the LOR in the evaluation of resident applicants. The use of a standardized LOR based on our PPQ concept has other inherent advantages.The authors thank Mark Langdorf, MD, Harold Thomas, MD, and Richard Wolfe. MD, for their participation in reviewing the letters of recommendation and preprinted questionnaires, and Velma Richmond for her assistance in the preparation of the manuscript. I REFERENCES Wound Botulism Associated with Black Tar HeroinMichael W Anderson, MD, Kanika Shama, MD, Colin M. Feeney, MD I ABSTRACTThe incidence of wound botulism is increasing and the epidemiology of the disease is changing. The majority of new cases are associated with injection drug use, in particular, the use of Mexican black tar heroin. This case report and discussion of wound botulism illustrate the following important points: Dysphagia, dysphonia, diplopia, and descending paralysis, in association with injection drug use, should alert the treating physician to the possibility of wound botulism. In such patients, the onset of respiratory failure may be sudden and without clinically obvious signs of respiratory weakness. For the reported patient, maximum inspiratory force measurements were the only reliable indicator of respiratory muscle weakness. This is a measurement not routinely performed in the ED, but may prove essential for patients with suspected wound botulism. To minimize the effect of the botulinum toxin and to decrease length of hospital stay, antitoxin administration and surgical wound debridement should be performed early.

show abstract

Wound botulism

Cited by 34 publications

References 16 publications

Clinical spectrum of botulism

Clinical spectrum of botulism

Wound botulism in drug addicts in the United Kingdom

Wound Botulism Associated with Black Tar Heroin

Contact Info

Product

Resources

About