“…Most of the modeling studies on wound healing consider only one partial process. The papers on continuum hypothesis-based models for wound healing can be classified into -models for contraction, for instance the work by Olsen et al (1995), Murray (2004), Vermolen (2009), where both mechanistic effects from pulling forces exerted by (myo-)fibroblasts, proliferation, cell mobility and chemical interactions are dealt with; -models for wound angiogenesis, in which we mention, among many others, the studies carried out by Maggelakis (2004), Schugart et al (2008), Xue et al (2009), andGaffney (2002). In some of these studies, the shortage of oxygen is taken into account as a trigger for angiogenesis.…”