Would coronary collaterals to the infarct-related artery serve as a marker of viability in patients with prior myocardial infarction? A study with trimetazidine-99mTc-sestamibi imaging

Adel, Amr; Mohamed, Asmaa S.; Nammas, Wail

doi:10.1016/j.carrev.2009.11.004

Cited by 2 publications

(2 citation statements)

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“…In patients presenting MI, some previous reports demonstrate that a high degree of collateralization to the IRA is related to a reduced infarct burden and myocardial savage, improving prognosis [8][9][10][11][12][13]. Nevertheless, other studies have failed to demonstrate any benefits in terms of myocardial viability from CCC in MI patients [14,16,31].…”

Section: Coronary Collateral Circulation Effect On Myocardial Infarct...mentioning

confidence: 99%

“…Conversely, the extent of myocardial scar is associated with left ventricular remodeling and increased risk of sudden death [6]. Previous studies have shown conflicting results regarding the contribution of early coronary collateral circulation (CCC) to myocardial viability and function in the setting of MI and in other clinical scenarios [7][8][9][10][11][12][13][14]. But, of note, in the primary angioplasty era, the role of CCC in the setting of MI may have been influenced by the effect of early coronary reperfusion.…”

Section: Introductionmentioning

confidence: 99%

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Early recruitable coronary collaterals preserve miocardial viability in late presentation infarctions

Gutierrez-Barrios

Lastra

Cañadas-Pruaño

et al. 2022

Coronary Artery Disease

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Background Previous studies showed conflicting results regarding the contribution of coronary collateral circulation (CCC) to myocardial perfusion and function in the setting of myocardial infarction (MI). In the primary angioplasty era, the role of CCC in these studies may have been influenced by the effect of early reperfusion. The true impact of CCC could be clarified by studying its effect on nonreperfused patients. The aim of our study was to evaluate the effect of CCC on myocardial viability of late presentation MI. Methods and resultsBetween 2008 and 2019, we included 167 patients with a late presentation MI who had a complete angiographic occlusion in a major coronary artery in which myocardial viability of the culprit territory was assessed. Patients were divided according to the presence of angiographic early recruited CCC (ERCC) (Rentrop 2-3) or poor CCC (PCC) (Rentrop 0-1). A lower left ventricular ejection function (LVEF) at discharge (54.2 ± 9 vs. 47.9 ± 12; <0.01) and a more severe left ventricular wall motion abnormalities in the culprit territory were observed in PCC patients. The presence of ERCC was the main independent predictor of myocardial viability in late presentation MI (hazard ratio, 4.24; 95% confidence interval, 1.68-10.6; P < 0.001). At follow-up, wall motion score increased significantly (2.05 ± 0.16; P = 0.02) in patients with ERCC but not in PCC patients (0.07 ± 0.16; P = 0.4), and LVEF improvement was significantly higher in ERCC than in PCC patients (9.7 ± 2.6 vs. 3.8 ± 4.2; P = 0.02). ConclusionThe presence of ERCC was the main independent predictor of myocardial viability in late presentation MI.

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Section: Coronary Collateral Circulation Effect On Myocardial Infarct...mentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

Early recruitable coronary collaterals preserve miocardial viability in late presentation infarctions

Gutierrez-Barrios

Lastra

Cañadas-Pruaño

et al. 2022

Coronary Artery Disease

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The collateral circulation of the heart in coronary total arterial occlusions in man: Systematic review of assessment and pathophysiology

Khand

Fisher

Jones

et al. 2013

American Heart Journal

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Would coronary collaterals to the infarct-related artery serve as a marker of viability in patients with prior myocardial infarction? A study with trimetazidine-99mTc-sestamibi imaging

Cited by 2 publications

References 28 publications

Early recruitable coronary collaterals preserve miocardial viability in late presentation infarctions

Early recruitable coronary collaterals preserve miocardial viability in late presentation infarctions

The collateral circulation of the heart in coronary total arterial occlusions in man: Systematic review of assessment and pathophysiology

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