2013
DOI: 10.3928/00485713-20130806-06
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Worsening Depression in a Patient with a Granulosa Cell Tumor

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“…These receptors are mainly expressed in the hypothalamus and amygdala [43,44,105], areas related in autonomic function and emotional regulation [34,106]. Genetic variation in the estrogen receptors may modify estrogen signaling, thus influencing a woman’s susceptibility to developing depression [107]. A study conducted on Chinese women diagnosed with major depression and healthy controls found that women carrying the genotype PP of the PvuII SNP had a higher risk of major depression compared to women with the Pp or pp genotype [108].…”
Section: Discussionmentioning
confidence: 99%
“…These receptors are mainly expressed in the hypothalamus and amygdala [43,44,105], areas related in autonomic function and emotional regulation [34,106]. Genetic variation in the estrogen receptors may modify estrogen signaling, thus influencing a woman’s susceptibility to developing depression [107]. A study conducted on Chinese women diagnosed with major depression and healthy controls found that women carrying the genotype PP of the PvuII SNP had a higher risk of major depression compared to women with the Pp or pp genotype [108].…”
Section: Discussionmentioning
confidence: 99%