Worldwide Evolution of Vaccinable and Nonvaccinable Viral Skin Infections: Google Trends Analysis

Abstract

Background Most common viral skin infections are not reportable conditions. Studying the population dynamics of these viral epidemics using traditional field methods is costly and time-consuming, especially over wide geographical areas. Objective This study aimed to explore the evolution, seasonality, and distribution of vaccinable and nonvaccinable viral skin infections through an analysis of Google Trends. Methods Worldwide search trends from January 2004 through May 2021 for viral skin infections were extracted from Google Trends, quantified, and analyzed. Results Time series decomposition showed that the total search term volume for warts; zoster; roseola; measles; hand, foot, and mouth disease (HFMD); varicella; and rubella increased worldwide over the study period, whereas the interest for Pityriasis rosea and herpes simplex decreased. Internet searches for HFMD, varicella, and measles exhibited the highest seasonal patterns. The interest for measles and rubella was more pronounced in African countries, whereas the interest for HFMD and roseola was more pronounced in East Asia. Conclusions Harnessing data generated by web searches may increase the efficacy of traditional surveillance systems and strengthens the suspicion that the incidence of some vaccinable viral skin infections such as varicella, measles, and rubella may be globally increasing, whereas the incidence of common nonvaccinable skin infections remains stable.

The non-stationary and spatially varying associations between hand, foot and mouth disease and multiple environmental factors: A Bayesian spatiotemporal mapping model study

“…The virus has been found in the excreta, herpes fluid, and respiratory secretions of confirmed HFMD cases and those with latent infection, and further spread to other susceptible people through fecal-oral transmission, droplets, and contact with contaminated objects. The incubation period of HFMD generally experiences 2–10 days and the incidence of HFMD has obvious seasonal characteristics ( Simonart, Lam Hoai, & De Maertelaer, 2022 ). Severe epidemics and outbreaks of HFMD in the Western Pacific region and East Asian countries have resulted in a heavy health and economic burden.…”