World Health Organization 5-item well-being index: validation of the Brazilian Portuguese version

Abstract

The psychological well-being dimension and depressive symptoms are both important variables in an individual's health. In this study, we evaluated the World Health Organization 5-item well-being index (WHOFive) internal and external validities, and accuracy in detecting depression. A total of 1,128 individuals between 18 and 65 years old from a rural Brazilian population were included. Cronbach's alpha and factor analysis were performed for internal validation. Demographic variables means were compared, receiver operating characteristic (ROC) curve was constructed, and sensitivity, specificity and positive and negative predictive values for different cutoff points were calculated for external validation and accuracy in detecting depression. Cronbach's alpha was 0.83, and only one factor was responsible for 59% of common variances, with an eigenvalue of 2.96. Higher WHO-Five scores were associated with being man, from oldest age category and retired. It was also related to better general health selfperception and negative screening in the Beck Depression Inventory (BDI). Based on BDI, the area under the curve was 67.37. A sensitivity of 66/75% and a negative predictive value of 91/92% for cutoffs <19/20 were detected. WHO-Five showed internal and external validities when used to measure the well-being dimension and to be a useful tool for depression screening.

Impact of water hardness on oxytetracycline oral bioavailability in fed and fasted piglets

“…The possibility of providing therapy to a large number of animals minimizing labour requirements are known benefits over injectable use. However, after oral administration, drugs might not be properly absorbed leading to therapeutic failures, increased bacterial resistance and antibiotic residues accumulation in the environment (Cromwell, 2002;de Souza & Hidalgo, 1997;Wegener, 2003). Medication through feed is generally the DOI: 10.1002/vms3.185…”

Role of Sirtuins in Linking Metabolic Syndrome with Depression

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Prospective Assessment of Daily Patterns of Mood-Related Symptoms

“…To ensure participants compliance, we met them on day 8 to collect the first week of the MRI-d data and handed the material for the last 7 days. On the 15th day, the remaining MRI-d material was collected, and they were asked to complete the MRI, Beck Depression Inventory [BDI, Beck et al ( 17 )], the World Health Organization 5-item well-being index [WHO-5, Bech ( 18 ); de Souza and Hidalgo ( 19 )] on the next day. Paper-based questionnaires were used.…”