Objective
To test the feasibility and preliminary effectiveness of the SB-PACT program, which includes directly observed therapy of preventive asthma medications in school facilitated by web-based technology for systematic symptom screening, electronic report generation, and medication authorization from providers.
Study design
We conducted a pilot randomized trial of SB-PACT vs. usual care with 100 children (ages 3-10yrs) from 19 inner-city schools in Rochester, NY. Outcomes were assessed longitudinally by blinded interviewers. Analyses included bivariate statistics and linear regression models, adjusting for baseline symptoms.
Results
99 subjects had data for analysis. We screened all children using the web-based system, and 44/49 treatment children received directly observed therapy as authorized by their providers. Treatment children received preventive medications 98% of the time they were in school. Over the school year, children in the treatment group experienced nearly 1 additional symptom-free day/two weeks vs. usual care (11.33 vs. 10.40,p=.13). Treatment children also experienced fewer symptom nights (1.68 vs. 2.20,p=.02), days requiring rescue medications (1.66 vs. 2.44,p=.01) and days absent from school due to asthma (.37 vs. .85,p=.03) compared with usual care. Further, treatment children had a greater decrease in exhaled nitric oxide (−9.62 vs. −.39,p=.03), suggesting reduction in airway inflammation.
Conclusion
The SB-PACT intervention demonstrated feasibility and improved outcomes across multiple measures in this pilot study. Future work will focus on further integration of preventive care delivery across community and primary care systems.