Working Memory Training and Cortical Arousal in Healthy Older Adults: A Resting-State EEG Pilot Study

Spironelli, Chiara; Borella, Erika

doi:10.3389/fnagi.2021.718965

Cited by 6 publications

(5 citation statements)

References 59 publications

(91 reference statements)

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“…The reliability in both age groups was equivalent, within the a priori determined boundaries of (+ − 0.2 ICC, Figure 4). This is important because it documents the excellent test-retest reliability of EEG-derived dependent metrics as a requirement for example in cognitive remediation therapies in aging research (e.g., Spironelli & Borella, 2021;Volf et al, 2018). However, despite good reliability, the utility of other frequency bands during awake rest, such as delta, theta, and gamma, in not only revealing consistent group differences but also with respect to their interpretation in terms of brain function, should be taken with care.…”

Section: Yes Nomentioning

confidence: 99%

Test–retest reliability of resting‐state EEG in young and older adults

et al. 2023

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The quantification of resting‐state electroencephalography (EEG) is associated with a variety of measures. These include power estimates at different frequencies, microstate analysis, and frequency‐resolved source power and connectivity analyses. Resting‐state EEG metrics have been widely used to delineate the manifestation of cognition and to identify psychophysiological indicators of age‐related cognitive decline. The reliability of the utilized metrics is a prerequisite for establishing robust brain–behavior relationships and clinically relevant indicators of cognitive decline. To date, however, test–retest reliability examination of measures derived from resting human EEG, comparing different resting‐state measures between young and older participants, within the same adequately powered dataset, is lacking. The present registered report examined test–retest reliability in a sample of 95 young (age range: 20–35 years) and 93 older (age range: 60–80 years) participants. A good‐to‐excellent test–retest reliability was confirmed in both age groups for power estimates on both scalp and source levels as well as for the individual alpha peak power and frequency. Partial confirmation was observed for hypotheses stating good‐to‐excellent reliability of microstates measures and connectivity. Equal levels of reliability between the age groups were confirmed for scalp‐level power estimates and partially so for source‐level power and connectivity. In total, five out of the nine postulated hypotheses were empirically supported and confirmed good‐to‐excellent reliability of the most commonly reported resting‐state EEG metrics.

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Section: Yes Nomentioning

confidence: 99%

Test–retest reliability of resting‐state EEG in young and older adults

et al. 2023

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“…Similarly, categorization tasks have been employed in complex span tests, commonly used for assessing individual differences in WM capacity. The Categorization Working Memory Span Test (CWMST), which incorporates such tasks, effectively assesses WM capacity (Spironelli & Borella, 2021; Spironelli et al, 2020).…”

Section: Discussionmentioning

confidence: 99%

The arousal level of consciousness required for working memory performance: An anaesthesia study

Osaka,

Minamoto,

Ikeda

et al. 2024

Eur J of Neuroscience

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Regarding the stage of arousal level required for working memory to function properly, limited studies have been conducted on changes in working memory performance when the arousal level of consciousness decreases. This study aimed to experimentally clarify the stages of consciousness necessary for optimal working memory function. In this experiment, the sedation levels were changed step‐by‐step using anaesthesia, and the performance accuracy during the execution of working memory was assessed using a dual‐task paradigm. Participants were required to categorize and remember words in a specific target category. Categorization performance was measured across four different sedative phases: before anaesthesia (baseline), and deep, moderate and light stages of sedation. Short‐delay recognition tasks were performed under these four sedative stages, followed by long‐delay recognition tasks after participants recovered from sedation. The results of the short‐delay recognition task showed that the performance was lowest at the deep stage. The performance of the moderate stage was lower than the baseline. In the long‐delay recognition task, the performance under moderate sedation was lower than that under baseline and light sedation. In addition, the performance under light sedation was lower than that under baseline. These results suggest that task performance becomes difficult under half sedation and that transferring information to long‐term memory is difficult even under one‐quarter sedation.

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“…In a past experiment co-measuring PET and EEG in a healthy sample at rest, greater global and voxel-wise positive correlation was found between high frequency EEG bands (namely high-beta and gamma) and brain metabolism, whereas alpha EEG band showed the greatest negative correlation [26]. The combination of alpha and beta EEG bands (beta/alpha ratio) adopted in the present study allows to maximize the most activated cortical regions and, at the same time, normalizes the spectral activation across subjects (as the ratio indicates a percentage of beta over alpha amplitude [51]) so that individuals with greater spectral energy do not weigh more statistically than those with smaller energy.…”

Section: Experimental Procedures and Data Analysismentioning

confidence: 91%

“…Thus, for statistical purposes, we calculated an activation index [51] as the ratio between high-beta (in the text indicated for simplicity as beta only; 20-35 Hz, effective β range = 20.50-35.14 Hz) and alpha bands (8-12 Hz, effective α range = 8.30-11.71 Hz) on F7 and F8 electrodes. Therefore, the statistical analysis included the group factor (three levels: EBD vs. MDD vs. PDD) and the site factor (two levels: F7 vs. F8).…”

Section: Experimental Procedures and Data Analysismentioning

confidence: 99%

EEG Frontal Asymmetry in Dysthymia, Major Depressive Disorder and Euthymic Bipolar Disorder

et al. 2021

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In the last few decades, the incidence of mood disorders skyrocketed worldwide and has brought an increasing human and economic burden. Depending on the main symptoms and their evolution across time, they can be classified in several clinical subgroups. A few psychobiological indices have been extensively investigated as promising markers of mood disorders. Among these, frontal asymmetry measured at rest with quantitative EEG has represented the main available marker in recent years. Only a few studies so far attempted to distinguish the features and differences among diagnostic types of mood disorders by using this index. The present study measured frontal EEG asymmetry during a 5-min resting state in three samples of patients with bipolar disorder in a Euthymic phase (EBD, n = 17), major depressive disorder (MDD, n = 25) and persistent depressive disorder (PDD, n = 21), once termed dysthymia. We aimed to test the hypothesis that MDD and PDD lack the typical leftward asymmetry exhibited by normal as well as EBD patients, and that PDD shows greater clinical and neurophysiological impairments than MDD. Clinical scales revealed no symptoms in EBD, and significant larger anxiety and depression scores in PDD than in MDD patients. Relative beta (i.e., beta/alpha ratio) EEG asymmetry was measured from lateral frontal sites and results revealed the typical greater left than right frontal beta activity in EBD, as well as a lack of asymmetry in both MDD and PDD. The last two groups also had lower bilateral frontal beta activity in comparison with the EBD group. Results concerning group differences were interpreted by taking into account both the clinical and the neurophysiological domains.

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Working Memory Training and Cortical Arousal in Healthy Older Adults: A Resting-State EEG Pilot Study

Cited by 6 publications

References 59 publications

Test–retest reliability of resting‐state EEG in young and older adults

Test–retest reliability of resting‐state EEG in young and older adults

The arousal level of consciousness required for working memory performance: An anaesthesia study

EEG Frontal Asymmetry in Dysthymia, Major Depressive Disorder and Euthymic Bipolar Disorder

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