Working Memory Impairment Across Psychotic disorders

Gold, James M.; Deanna, M; Feuerstahler, Leah; Carter, Cameron S.; MacDonald, Angus W.; Ragland, J. Daniel; Silverstein, Steven M.; Strauss, Milton E.; Luck, Steven J.

doi:10.1093/schbul/sby134

Cited by 54 publications

(49 citation statements)

References 45 publications

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“…Green et al note this, but focus somewhat more on the differences across disorders than on the similarities. One could argue that the most robust evidence indicates similar profiles of cognitive impairment across disorders that involve psychosis, including schizophrenia, schizoaffective disorder, bipolar disorder with psychosis, and even psychotic depression. The severity of these deficits often vary across illnesses, with the most severe in schizophrenia, but the general pattern is often remarkably similar.…”

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confidence: 99%

“…One could argue that the most robust evidence indicates similar profiles of cognitive impairment across disorders that involve psychosis, including schizophrenia, schizoaffective disorder, bipolar disorder with psychosis, and even psychotic depression. The severity of these deficits often vary across illnesses, with the most severe in schizophrenia, but the general pattern is often remarkably similar. Moreover, there is also evidence for impairment in at least some cognitive domains in a host of other forms of psychopathology, including non‐psychotic major depression and attention‐deficit/hyperactivity disorder.…”

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confidence: 99%

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Nonsocial and social cognitive function in psychosis: interrelationships, specificity and innovative approaches

Deanna

2019

World Psychiatry

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confidence: 99%

mentioning

confidence: 99%

Nonsocial and social cognitive function in psychosis: interrelationships, specificity and innovative approaches

Deanna

2019

World Psychiatry

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“…WM has also been noted as a predictor of occupational functioning [3] and has been related to improvements in psychological functioning following cognitive remediation [4] in individuals with psychotic disorders. Despite the extensive literature related to WM dysfunction in this population, there remains considerable debate regarding how best to measure this cognitive domain [5,6].…”

Section: Introductionmentioning

confidence: 99%

Comparison of the touch-screen and traditional versions of the Corsi block-tapping test in patients with psychosis and healthy controls

et al. 2020

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Background: Working memory (WM) refers to the capacity system for temporary storage and processing of information, which is known to depend on the integrity of the prefrontal cortex. Impairment in working memory is a core cognitive deficit among individuals with psychotic disorders. The Corsi block-tapping test is a widely-used instrument to assess visuospatial working memory. The traditional version is composed of 9 square blocks positioned on a physical board. In recent years, the number of digital instruments has increased significantly; several advantages might derive from the use of a digital version of the Corsi test. Methods: This study aimed to compare the digital and traditional versions of the Corsi test in 45 patients with psychotic disorders and 45 healthy controls. Both groups completed a neuropsychological assessment involving attention and working memory divided into the two conditions. Results: Results were consistent between the traditional and digital versions of the Corsi test. The digital version, as well as the traditional version, can discriminate between patients with psychosis and healthy controls. Overall, patients performed worse with respect to the healthy comparison group. The traditional Corsi test was positively related to intelligence and verbal working memory, probably due to a more significant effort to execute the test. Conclusions: The digital Corsi might be used to enhance clinical practice diagnosis and treatment.The digital version can be administered in a natural environment in real-time. Further, it is easy to administer while ensuring a standard procedure.

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“…WM has also been noted as a predictor of occupational functioning (3) and has been related to improvements in psychological functioning following cognitive remediation (4) in individuals with psychotic disorders. Despite the extensive literature related to WM dysfunction in this population, there remains considerable debate regarding how best to measure this cognitive domain (5,6).…”

Section: Introductionmentioning

confidence: 99%

Comparison of the touch-screen and traditional versions of the Corsi block-tapping test in patients with psychosis and healthy controls.

Siddi

Preti

Lara

et al. 2019

Preprint

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Working memory (WM) refers to the capacity system for temporary storage and processing of information, which is known to depend on the integrity of the prefrontal cortex. Impairment in working memory is a core cognitive deficit among individuals with psychotic disorders. The Corsi block-tapping test is a widely used instrument to assess visuospatial working memory. The traditional version is composed of 9 square blocks positioned on a physical board. In recent years, the number of digital instruments has increased significantly; several advantages might derive from the use of a digital version of the Corsi test. This study aimed to compare the digital and traditional versions of the Corsi test in 45 patients with psychotic disorders and 45 healthy controls. Both groups completed a neuropsychological assessment involving attention and working memory divided into two conditions. Results were consistent between the traditional and digital versions of the Corsi test. Overall, patients performed worse relative to the healthy comparison group. The traditional Corsi test was positively related to intelligence and verbal working memory, probably due to a more significant effort to execute the test. The digital version is able to discriminate between patients with psychosis and healthy controls. It would be of use in determining who is at risk of developing a psychotic disorder, and in those already with psychosis, it might provide a prognostic marker for future functional outcome. Further, it is easy to administer while ensuring a standard procedure.

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Working Memory Impairment Across Psychotic disorders

Cited by 54 publications

References 45 publications

Nonsocial and social cognitive function in psychosis: interrelationships, specificity and innovative approaches

Nonsocial and social cognitive function in psychosis: interrelationships, specificity and innovative approaches

Comparison of the touch-screen and traditional versions of the Corsi block-tapping test in patients with psychosis and healthy controls

Comparison of the touch-screen and traditional versions of the Corsi block-tapping test in patients with psychosis and healthy controls.

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