Workers with Obstructive Sleep Apnea Syndrome: Proposal of a Clinical-Anamnestic Tool for the Occupational Health Surveillance

Martini, Agnese; Luzzi, Valeria; Pietrafesa, Emma; Carlo, Gabriele Di; Guaragna, Mariana; Mazur, Marta; Cotticelli, Luisa; Giacomo, Paola Di; Piperno, G.; Brunori, Marco; Paolo, Carlo Di; Polimeni, Antonella

doi:10.1016/j.shaw.2021.12.1109

Cited by 2 publications

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“…Motor vehicle crash risk can be attributed to sleepiness and impaired vigilance conditions [ 1 ]. Obstructive sleep apnea syndrome (OSAS) is an under-recognized clinical condition and is correlated with sleepiness and impaired cognitive function [ 1 , 2 , 3 , 4 , 5 , 6 , 7 , 8 ].…”

Section: Introductionmentioning

confidence: 99%

Correlations of Obstructive Sleep Apnea Syndrome and Daytime Sleepiness with the Risk of Car Accidents in Adult Working Population: A Systematic Review and Meta-Analysis with a Gender-Based Approach

Luzzi

Mazur

Guaragna

et al. 2022

JCM

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Obstructive sleep apnea syndrome (OSAS) is an under-recognized clinical condition and is correlated with sleepiness and impaired cognitive function. Objectives: The primary aim of this systematic review, developed within the Sleep@OSA project, was to determine the correlations of obstructive sleep apnea syndrome, daytime sleepiness and sleep-disordered breathing with the risk of car accidents in adult working populations; a secondary aim was to analyze the epidemiologic data with a gender-based approach to identify differences between women and men in the data and in associated risk factors. Methods: Clinical trials and studies reporting data on the frequency of car accidents involving adult working population with daytime sleepiness and/or OSAS compared with a control group of participants were included. Literature searches of free text and MeSH terms were performed using PubMed, Google Scholar, the Cochrane Library and Scopus from 1952 to 3 May 2021. Results and Conclusions: The search strategy identified 2138 potential articles. Of these, 49 papers were included in the qualitative synthesis, and 30 were included in the meta-analysis. Compared with controls, the odds of car accidents were found to be more than double in subjects with OSAS (OR = 2.36; 95% CI 1.92–2.91; p < 0.001), with a similar risk between commercial motor vehicle drivers (OR = 2.80; 95% CI 1.82–4.31) and noncommercial motor vehicle drivers (OR = 2.32; 95% CI 1.84–2.34). No significant correlation was found between sleepiness and car crashes, but subjects with sleep-disordered breathing were at increased risk of car accidents (OR = 1.81; 95% CI 1.42–2.31; p < 0.001). To our surprise, although epidemiological studies on the risk of road accidents in the adult population with OSAS and daytime sleepiness are currently very abundant, specific data on the female population are not available.

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Section: Introductionmentioning

confidence: 99%

Correlations of Obstructive Sleep Apnea Syndrome and Daytime Sleepiness with the Risk of Car Accidents in Adult Working Population: A Systematic Review and Meta-Analysis with a Gender-Based Approach

Luzzi

Mazur

Guaragna

et al. 2022

JCM

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Section: Discussionmentioning

confidence: 99%

“…Sasaki et al and Martini et al (22,23) studied vestibular end organs in the ischemic model by immunoelectron microscopy and found that if the duration of ischemia was 10 minutes, the glutamate levels in the type I and II hair cells and supporting cells of the vestibular decreased, but the morphological changes in the nerve extension and calyces dendrites were not significant. When the ischemia lasted for 30 minutes, the morphological changes were obvious, and the precondition neurons of the inner ear were irreversibly damaged (23,24). In OSAHS patients with neurootological diseases, the occlusion of the anterior inferior cerebellar artery is confirmed by pathology, which leads to labyrinthine artery ischemia and cerebellar ischemia, which can lead to central and peripheral vertigo, acute vestibular syndrome, and unilateral hearing loss.…”

Section: Discussionmentioning

confidence: 99%

Clinical case control study analysis of vestibular function in patients with obstructive sleep apnea-hypopnea syndrome

Li¹,

Chen²,

Liang³

et al. 2022

Ann Palliat Med

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Background: To investigate the effects of hypoxia degree and sleep duration on vestibular function in obstructive sleep apnea-hypopnea syndrome (OSAHS) patients. We made further study the low oxygen levels of OSAHS and hypoxic duration on the impact of vestibular function, and further studied the OSAHS the longest apnea time and Vestibular Evoked Myogenic Potential (VEMP) abnormal rate and the relationship between the vestibular function of canal paralysis (CP).Methods: A total of 87 OSAHS patients and 47 healthy individuals were enrolled in this study. There was no difference in gender, age and BMI values in matched experimental groups. Exclude other diseases of other system. All the participants completed sleepiness questionnaires (i.e., the Epworth sleepiness scale and the STOP-BANG questionnaire) and the Dizziness Handicap Inventory (DHI). Additionally, a caloric test, positional test, electrocochleogram, and VEMP test were administered to evaluate the vestibular function of all the participants. A polysomnography (PSG) was also performed. Results:The current investigation generated the following three major findings: (I) there was a significant correlation between body mass index and canal paresis [CP; P=0.014, odds ratio (OR) =1.791, 95% confidence interval (CI): 1.125-2.851] and a significant positive correlation between the DHI score and VEMP results (P=0.0061, OR =3.667, 95% CI: 1.449-9.276); (II) the CP abnormality rate of the OSAHS group was significantly higher than that of the control group (P<0.05); (III) there was a significant correlation between the longest apnea duration and the DHI score (r=-0.191, P<0.05). Conclusions:The abnormality rate of the vestibular function of OSAHS patients is higher than that of healthy people. OSAHS intermittent hypoxia can affect vestibular function in the inner ear, and the longer the duration of prolonged hypoxia, the more serious the vestibular function damage.

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Workers with Obstructive Sleep Apnea Syndrome: Proposal of a Clinical-Anamnestic Tool for the Occupational Health Surveillance

Cited by 2 publications

References 0 publications

Correlations of Obstructive Sleep Apnea Syndrome and Daytime Sleepiness with the Risk of Car Accidents in Adult Working Population: A Systematic Review and Meta-Analysis with a Gender-Based Approach

Correlations of Obstructive Sleep Apnea Syndrome and Daytime Sleepiness with the Risk of Car Accidents in Adult Working Population: A Systematic Review and Meta-Analysis with a Gender-Based Approach

Clinical case control study analysis of vestibular function in patients with obstructive sleep apnea-hypopnea syndrome

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