Work Productivity in Relapsing Multiple Sclerosis: Associations with Disability, Depression, Fatigue, Anxiety, Cognition, and Health-Related Quality of Life

Glanz, Bonnie I.; Dégano, Irene R.; Rintell, David; Chitnis, Tanuja; Weiner, Howard L.; Healy, Brian C.

doi:10.1016/j.jval.2012.07.010

Cited by 135 publications

(141 citation statements)

References 46 publications

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“…Presenteeism seems to be common among IBD employed patients because it was similarly reported in a Hungarian study in 60% of IBD patients, leading to a 28% loss of work productivity and a 32% activity loss [7]. Presenteeism can also have a severe negative impact on patients' life because it is associated with reduced QoL [27]. Moreover, IBD patients in our study without paid employment reported lower QoL and higher anxiety and depression rates than those in paid employment, which is in line with earlier research from Norway [5].…”

Section: Work Difficultiesmentioning

confidence: 89%

Employment status, difficulties at work and quality of life in inflammatory bowel disease patients

Boer¹,

Evertsz

Stokkers

et al. 2016

European Journal of Gastroenterology &Amp; Hepatology

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aObjectives To assess employment status, difficulties at work and sick leave in inflammatory bowel disease (IBD) patients and their relation with sociodemographic and clinical factors, quality of life (QoL), and anxiety and depression. Materials and methods IBD patients attending an IBD outpatients' clinic received self-report questionnaires on employment status, IBD-related difficulties at work and sick leave (Trimbos/iMTA questionnaire for Costs associated with Psychiatric Illness), sociodemographic factors, QoL (Inflammatory Bowel Disease Questionnaire and 12-item Short-form Health Survey) and anxiety and depression (Hospital Anxiety and Depression Scale). Disease activity was assessed by their gastroenterologist. Associations between paid employment and sick leave with sociodemographic and clinical factors, QoL and anxiety and depression were assessed by regression analyses. Results In total, 202 IBD patients of working age, with a mean age of 41 years, participated; 63% had Crohn's disease and 37% had ulcerative colitis, and 57% were women and 19% had active disease. In all, 123 (61%) patients were in paid employment, of whom 31 (25%) were on sick leave, whereas 46 (23%) received a disability pension. Concentration problems (72%), low working pace (78%) and delayed work production (50%) were the most prevalent IBD-related work difficulties. IBD patients without paid employment were older and more often women, with active disease, lower QoL and higher anxiety and depression rates. Sick leave was associated with lower QoL and higher anxiety and depression rates. Conclusion More than half of IBD patients were in paid employment, whereas almost a quarter was receiving a disability pension. A large majority experienced work difficulties. Having no paid employment was associated with poorer QoL and more anxiety and depression symptomatology. Eur

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Section: Work Difficultiesmentioning

confidence: 89%

Employment status, difficulties at work and quality of life in inflammatory bowel disease patients

Boer¹,

Evertsz

Stokkers

et al. 2016

European Journal of Gastroenterology &Amp; Hepatology

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“…Tapping Test, and of education, sex, and general disability. [6][7][8][9][10][11] Other MS symptom-related factors have also been found to predict employment status, including fatigue, 10,12 depression, [6][7][8] motor difficulties, 13 and cognitive problems. 14,15 More specifically, regarding cognitive problems, scores on tests of processing speed, verbal fluency, working memory, and long-term memory are typically lower in unemployed versus employed individuals with MS. 8,16,17 With all this said, research on cognition and depression has produced inconsistent findings.…”

Section: Methodsmentioning

confidence: 99%

Factors Associated with Employment Status in Individuals with Multiple Sclerosis

Cadden

Arnett

2015

International Journal of MS Care

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Background: Unemployment is common in individuals with multiple sclerosis (MS) and is associated with substantial socioeconomic burden. Several MS-related factors have been found to be associated with employment status, including fatigue, depression, cognitive problems, and motor difficulties. However, few studies have examined these factors collectively in predicting employment. The present study aimed to explore these variables together in predicting employment status in MS.

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“…1 It interferes with daily function, affects workload, and hampers interpersonal relationships, often leading to reduced quality of life. 2 Fatigue related to MS is multidimensional, consisting of this study was to explore the relationship between perceived fatigue, as measured using the NFI-MS, and performance fatigability in people with MS. Both perceived fatigue and fatigability interfere with the performance of household activities, can lead to deterioration in the performance of physical and cognitive tasks, and can worsen other symptoms, such as depression, sleepiness, and attention-related problems.…”

mentioning

confidence: 99%

Relationship Between Fatigability and Perceived Fatigue Measured Using the Neurological Fatigue Index in People with Multiple Sclerosis

Aldughmi¹,

Bruce²,

Siengsukon³

2017

International Journal of MS Care

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Background: Understanding the relationship between perceived fatigue and performance fatigability could lead to more effective interventions to manage multiple sclerosis (MS)-related fatigue. However, the relationship between self-perceived fatigue measured using the Neurological Fatigue Index (NFI-MS) and performance fatigability in people with MS is unknown. We sought to explore the relationship between the NFI-MS and performance fatigability in people with MS.

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Work Productivity in Relapsing Multiple Sclerosis: Associations with Disability, Depression, Fatigue, Anxiety, Cognition, and Health-Related Quality of Life

Cited by 135 publications

References 46 publications

Employment status, difficulties at work and quality of life in inflammatory bowel disease patients

Employment status, difficulties at work and quality of life in inflammatory bowel disease patients

Factors Associated with Employment Status in Individuals with Multiple Sclerosis

Relationship Between Fatigability and Perceived Fatigue Measured Using the Neurological Fatigue Index in People with Multiple Sclerosis

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