“…The test compounds selected are oleuropein and ligstroside aglycones, oleacein, oleocanthal, tyrosol, elenolic acid, luteolin, apigenin, pinoresinol, lariciresinol, isolariciresinol, verbascoside, o -coumaric acid and vanillic acid from extra-virgin olive oil [ 8 ], and the main dietary lignans namely matairesinol, secoisolariciresinol, pinoresinol, lariciresinol, medioresinol and syringaresinol [ 5 , 6 , 7 ]. Studies were done in comparison with anemonin, another very active neuroprotective and antitumor [ 26 , 27 , 28 , 29 ] symmetrical plant molecule, also composed of two identical monomers. In silico studies are completed with in vitro studies, punctuated with an evaluation of the cytotoxic and anti-proliferative activity of two ethanolic extracts from fresh and dried Anemone nemorosa L. aerial part ( herba et flores ), on normal and tumor human brain cells, on normal human astrocytes NHA and human glioma cell line U87, respectively.…”