Women with Diabetes Have Poorer Control of Blood Pressure Than Men

Duggirala, Murali K.; Cuddihy, Robert; Cuddihy, Maria-Teresa; Nyman, M.; Naessens, James M.; Pankratz, V. Shane

doi:10.1089/jwh.2005.14.418

Cited by 15 publications

(13 citation statements)

References 15 publications

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“…Therefore, DLM can be considered as the most severe comorbidity among men as well as middle-aged people with T2DM, suggesting that the control of dyslipidemia in middle-aged men is particularly important. In our study, differences in major macrocardiovascular risk factors (EH, CHD, and ACVD) in individuals with T2DM were slightly greater in men than women over time, which differs from the findings of previous studies [40–42]. EH and CHD, as two main chronic cardiovascular diseases, had similar changing trends in RCoR over time by sex and age.…”

Section: Resultscontrasting

confidence: 99%

Comorbidity in Adult Patients Hospitalized with Type 2 Diabetes in Northeast China: An Analysis of Hospital Discharge Data from 2002 to 2013

Chen

Zhang

et al. 2016

BioMed Research International

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This study aims to evaluate the comorbidity burden and patterns among adult patients hospitalized with a diagnosis of type 2 diabetes mellitus (T2DM) in Northeast China using hospital discharge data derived from the electronic medical record database between 2002 and 2013. 12.8% of 4,400,892 inpatients aged ≥18 had a diagnosis of T2DM. Sex differences in prevalence varied among those aged <50, 50–59, and ≥60. Twenty-seven diseases were determined as major comorbidities of T2DM. Essential hypertension was the most common comorbidity of T2DM (absolute cooccurrence risk, 58.4%), while T2DM was also the most popular comorbidity of essential hypertension. Peripheral and visceral atherosclerosis showed the strongest association (relative cooccurrence risk, RCoR 4.206). For five leading comorbidities among patients aged ≥40, male patients had a stronger association with disorders of lipid metabolism than female patients (RCoR 2.779 versus 2.099), and female patients had a stronger association with chronic renal failure than male patients (RCoR 2.461 versus 2.155). Leading comorbidities, except chronic renal failure, had declining associations with T2DM with increased age. Collectively, hospital discharge data can be used to estimate disease prevalence and identify comorbidities. The findings provided comprehensive information on comorbidity patterns, helping policy makers and programs in public health domains to estimate and evaluate the epidemic of chronic diseases.

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Section: Resultscontrasting

confidence: 99%

Comorbidity in Adult Patients Hospitalized with Type 2 Diabetes in Northeast China: An Analysis of Hospital Discharge Data from 2002 to 2013

Chen

Zhang

et al. 2016

BioMed Research International

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“…Thus, we did not confirm previous studies showing that men have lower HbA 1c levels and/or fewer episodes of ketonuria [21]. Such results were claimed to be a consequence of more intensive care for men [22].…”

Section: Discussioncontrasting

confidence: 97%

“…Here we report slightly lower DBP and higher HDL-cholesterol in women with type 2 diabetes, whereas other cardiovascular risk factors were identical in both sexes. Previous studies have found worse BP control, higher SBP [22] and higher LDLcholesterol in women patients [26]. It has therefore been suggested that women might be receiving lower-quality treatment [27], possibly contributing to their excess cardiovascular morbidity and mortality rates [3,28].…”

Section: Discussionmentioning

confidence: 99%

Sex-related psychological effects on metabolic control in type 2 diabetes mellitus

et al. 2009

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Aims/hypothesis Women are at higher risk of diabetesrelated cardiovascular complications than men. We tested the hypothesis that there are sex-specific differences in glucometabolic control, and in social and psychological factors. We also examined the influence of these factors on glucometabolic control. Methods We examined 257 (126 men/131 women) consecutive patients (64±9 years, means±SD) of a metropolitan diabetes outpatient service employing clinical testing and standardised psychological questionnaires. Results Mean HbA 1c (7.6±1.2%) was not different between women and men. Women patients on oral hypoglycaemic agents were better informed about diabetes (p=0.012). They employed more strategies for coping with diabetes, including religion (p=0.0001), active coping (p=0.048) and distraction (p=0.007). Women reported lower satisfaction with social support (p=0.034), but not more depression than men. Although no differences were observed in compliance, insulin-treated patients were more satisfied with their therapy (p=0.007). Variables predicting poor metabolic control were different in men (R 2 =0.737, p=0.012) and women (R 2 =0.597, p=0.019). Major predictors of high HbA 1c included depressive coping, lower sexual desire, quality of life and internal locus of control, but high external doctor-related locus of control in women and frequent emotional experiences of hyperglycaemia in men. Conclusions/interpretation Lower quality of life, internal control and socioeconomic status, and higher prevalence of negative emotions probably prevented woman patients from achieving improved glucose control despite their better knowledge of and greater efforts to cope with diabetes. We suggest that women patients would benefit from individualised diabetes care offering social support, whereas men would benefit from knowledge-based diabetes management giving them more informational and instrumental support.

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“…Similar results were found in a study carried by Cummings et al [36]. On the contrary Duggirala et al reported that female gender was a significant predictor of uncontrolled BP control in their study [37]. Moreover, other studies reported that gender was not associated with uncontrolled BP [33,34,38,39].…”

Section: Discussionsupporting

confidence: 81%

Factors Associated With Hypertension Prevalence and Control Among Lebanese Type 2 Diabetic Patients

Soubra

Nureddin

Omar

et al. 2016

Int J Pharm Pharm Sci

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Objective: The objectives of this study were to assess the prevalence of hypertension and the level of blood pressure (BP) control among a cohort of diabetic Lebanese patients on antihypertensive medications, as well as to identify factors associated with hypertension prevalence and uncontrolled BP. Methods:This cross-sectional retrospective study was conducted in a tertiary health care clinic that is specialized in the management and follow-up of diabetic outpatients.Results: Among the 700 type 2 diabetes mellitus patient files that were screened529 (75%) were found to have hypertension. Hypertension was more prevalent in women, patients aged ≥65-year-old, and those having a body mass index (BMI) of ≥30 (kg/m 2 Conclusion:Hypertension is prevalent among the study patients. However, attainment of BP control was poor among these patients. Therefore, there is a need for studies that determine reasons behind this low BP control rate in order to design interventions aiming at improving the standard of care for these patients.) (p-value<0.05). Among the hypertensive cohort, 465 T2DM were on antihypertensive medications and were included in the hypertension control analysis. Ninety-three patients (20%) attained BP control (SBP<140 and DBP<90 mmHg). Multivariate analyses revealed three factors that were significantly associated with uncontrolled BP control: Age being ≥65 y (adjusted OR = 1.96 (95% CI: 1.07-3.61, p-value<0.05), male gender (adjusted OR = 2.57, 95% CI: 1.41-4.66, p-value<0.05) and uncontrolled HDL (adjusted OR = 1.58, 95% CI: 1.33-2.01, p-value = 0.05).

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Women with Diabetes Have Poorer Control of Blood Pressure Than Men

Abstract: In subjects with diabetes receiving medical care, women had poorer control of blood pressure and a significantly higher mean SBP compared with men. These findings might partially explain the excess CHD mortality in women with diabetes.

Cited by 15 publications

References 15 publications

Comorbidity in Adult Patients Hospitalized with Type 2 Diabetes in Northeast China: An Analysis of Hospital Discharge Data from 2002 to 2013

Comorbidity in Adult Patients Hospitalized with Type 2 Diabetes in Northeast China: An Analysis of Hospital Discharge Data from 2002 to 2013

Sex-related psychological effects on metabolic control in type 2 diabetes mellitus

Factors Associated With Hypertension Prevalence and Control Among Lebanese Type 2 Diabetic Patients

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