Woman With Supposed Anaphylactic Reaction

Elangovan, Ashok; Chacko, Jose; Chatterjee, Somnath; Kuntoji, Basavaraj

doi:10.1016/j.annemergmed.2011.05.021

Cited by 1 publication

(3 citation statements)

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“…Out of 100 fully evaluated, 52 references were included in the analysis as per selection criteria. [ 13 14 15 16 17 18 19 20 21 22 23 24 25 26 27 28 29 30 31 32 33 34 35 36 37 38 39 40 41 42 43 44 45 46 47 48 49 50 51 52 53 54 55 56 57 58 59 60 61 62 63 64 ] The flow diagram for the article selection is presented as Figure 1 .…”

Section: Resultsmentioning

confidence: 99%

“…One study did not specify a setting. [ 23 ] As per “CARE guideline,” the most studies did not mention important timelines in the form of tables or figures, strengths, limitations, follow-up data and informed consent or permission from the institutional committee to publish the report. [ 9 ]…”

Section: Resultsmentioning

confidence: 99%

“…[ 19 33 36 37 46 49 53 ] One case did not mention the outcome. [ 23 ] The expired and survived cases showed no association with gender, set up, systems involved, route of administration for causative drugs and not administration of adrenaline. The expired cases were significantly associated with a high rate of complications, cerebral hypoxic damage and preventable reactions than survived cases [P < 0.05; [ Table 7 ].…”

Section: Resultsmentioning

confidence: 99%

See 2 more Smart Citations

Drug-induced anaphylactic reactions in Indian population: A systematic review

Patel¹,

Patel²,

Barvaliya³

et al. 2014

Indian Journal of Critical Care Medicine

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Background:Epidemiological data on drug-induced anaphylactic reactions are limited in India and are largely depending on studies from developed countries.Aim:The aim was to analyze the published studies of drug-induced anaphylaxis reported from India in relation with causative drugs and other clinical characteristics.Materials and Methods:The electronic databases were searched for Indian publications from 1998 to 2013 describing anaphylactic reactions. The information was collected for demographics, set up in which anaphylaxis occurred, causative drugs, incubation period, clinical features, associated allergic conditions, past reactions, co-morbid conditions, skin testing, IgE assays, therapeutic intervention and mortality. Reactions were analyzed for severity, causality, and preventability. Data were extracted and summarized by absolute numbers, mean (95% confidence interval [CI]), percentages and odds ratio (OR) (95% CI).Results:From 3839 retrieved references, 52 references describing 54 reactions were included. The mean age was 35.31 (95% CI: 30.52–40.10) years. Total female patients were 61.11%. Majority reactions were developed in perioperative conditions (53.70%), ward (20.37%) and home (11.11%). The major incriminated groups were antimicrobials (18.52%), nonsteroidal antiinflammatory drugs-(NSAIDs) (12.96%) and neuromuscular blockers (12.96%). Common causative drugs were diclofenac (11.11%), atracurium (7.41%) and β-lactams (5.96%). Cardiovascular (98.15%) and respiratory (81.48%) symptoms dominated the presentation. Skin tests and IgE assays were performed in 37.03% and 18.52% cases, respectively. The fatal cases were associated with complications (OR =5.04; 95% CI: 1.41–17.92), cerebral hypoxic damage (OR =6.80; 95% CI: 2.14–21.58) and preventable reactions (OR =14.33; 95% CI: 2.33–87.97).Conclusion:Antimicrobials, NSAIDs, and neuromuscular blockers are common causative groups. The most fatal cases can be prevented by avoiding allergen drugs.

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