Wolff-Parkinson-White syndrome

Chung, Koo-Young; Walsh, Thomas J.; Massie, Edward

doi:10.1016/0002-8703(65)90224-3

Cited by 179 publications

(22 citation statements)

References 64 publications

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“…The sentiment reflects a nearly 30% to 40% incidence of AF in WPW patients compared with long-term rates in non-WPW patients that are <10%. [6][7][8] However, now that catheter ablation for WPW has been used for multiple decades, an understanding of very long-term outcomes is possible, including risk of AF. In our center, we have observed many patients with prior ablation for WPW returning for management of AF.…”

mentioning

confidence: 99%

Long-Term Natural History of Adult Wolff–Parkinson–White Syndrome Patients Treated With and Without Catheter Ablation

Bunch

May

Bair

et al. 2015

Circ: Arrhythmia and Electrophysiology

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Background-There are a paucity of data about the long-term natural history of adult Wolff-Parkinson-White syndrome (WPW) patients in regard to risk of mortality and atrial fibrillation. We sought to describe the long-term outcomes of WPW patients and ascertain the impact of ablation on the natural history. Methods and Results-Three groups of patients were studied: 2 WPW populations (ablation: 872, no ablation: 1461) and a 1:5 control population (n=11 175). Long-term mortality and atrial fibrillation rates were determined. The average followup for the WPW group was 7.9±5.9 (median: 6.9) years and was similar between the ablation and nonablation groups. Death rates were similar between the WPW group versus the control group (hazard ratio, 0.96; 95% confidence interval, 0.83-1.11; P=0.56). Nonablated WPW patients had a higher long-term death risk compared with ablated WPW patients (hazard ratio, 2.10; 95% confidence interval: 1.50-20.93; P<0.0001). Incident atrial fibrillation risk was higher in the WPW group compared with the control population (hazard ratio, 1.55; 95% confidence interval, 1.29-1.87; P<0.0001). Nonablated WPW patients had lower risk than ablated patients (hazard ratio, 0.39; 95% confidence interval, 0.28-0.53; P<0.0001). Conclusions-Long-term mortality rates in WPW patients are low and similar to an age-matched and gender-matched control population. WPW patients that underwent the multifactorial process of ablation had a lower mortality compared to nonablated WPW patients. Atrial fibrillation rates are high long-term, and ablation does not reduce this risk.

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mentioning

confidence: 99%

Long-Term Natural History of Adult Wolff–Parkinson–White Syndrome Patients Treated With and Without Catheter Ablation

Bunch

May

Bair

et al. 2015

Circ: Arrhythmia and Electrophysiology

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“…The prevalence of Wolff Parkinson White syndrome in the adult population is approximately 0.3%. 14 In the current study, three patients (1.5%) showed the ECG features of Wolff Parkinson White syndrome but all were asymptomatic with no history of palpitation. In a healthy adult, this implies that the accessory pathway does not have the electrophysiological characteristics to allow the development of supraventricular tachycardia and therefore can be ignored.…”

Section: Screening Visit Abnormalitiesmentioning

confidence: 45%

ECG variations in patients pre- and post-local anaesthesia and analgesia

Hill¹,

Mostafa²,

Stuart

et al. 2009

Br Dent J

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“…L aham [1969] and G iraud el al. [1956] have stressed that during tachy cardia (especially in patients with atrial fibrillation), the A-V conduction proceeds through the bundle of His, and therefore characteristic changes of WPW syndrome disappear [Chung et al, 1965;W olff, 1954;Y eh in i, 1964], The present case is interesting in that the electrocardiogram displays a wide QRS configuration during atrial fibrillation as well as during sinus rhythm. It has been demonstrated by Schuilenburg and D urrer [1972] that the lower limit of the functional refractory period of the A-V node is 0.33 sec.…”

Section: Discussionmentioning

confidence: 69%

“…However, atrial fibrillation and atrial flutter are thought to be uncommon in cases of WPW syndrome (Wolff et al, 1930; L angendorf et al, 1952; W o lff, 1954; A verili. et al, 1960; C hung et al, 1965], When they do occur they are usually observed in patients with the type A of WPW syndrome [Chung et al, 1965]. Only a few reports have described atrial fibrillation or atrial flutter associated with type B [M andel, 1961 ; Y ehini et al, 1964: L o e w .…”

mentioning

confidence: 99%

Paroxysmal Atrial Fibrillation in Wolff-Parkinson-White Syndrome, Type B

Kerin¹,

Davies²,

Kopelson³

et al. 1973

Cardiology

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In a case of Wolff-Parkinson-White syndrome, type B, the electrocardiogram displayed the same broad QRS configuration during an episode of paroxysmal atrial fibrillation as during normal sinus rhythm, suggesting conduction via an accessory atrioventricular connection. The incidence of atrial fibrillation and atrial flutter in type B of Wolff-Parkinson-White syndrome may not be as rare as it was once thought to be.

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Wolff-Parkinson-White syndrome

Cited by 179 publications

References 64 publications

Long-Term Natural History of Adult Wolff–Parkinson–White Syndrome Patients Treated With and Without Catheter Ablation

Long-Term Natural History of Adult Wolff–Parkinson–White Syndrome Patients Treated With and Without Catheter Ablation

ECG variations in patients pre- and post-local anaesthesia and analgesia

Paroxysmal Atrial Fibrillation in Wolff-Parkinson-White Syndrome, Type B

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