Wobbler Facility for Biomedical Experimenis at the Bevalac

Chu, W. T.; Curtis, Stanley B.; Llacer, J.; Renner, T.; Sorensen, Royal W.

doi:10.1109/tns.1985.4334356

Cited by 16 publications

(8 citation statements)

References 2 publications

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“…The centrifuge tubes were vertically irradiated with 12 C +6 ion beams (135 MeV/nucleon, about 50% of speed of light) accelerated by RIKEN ring cyclotron (RRC) at doses of 25, 50, 100, 150, 200, 300 and 400 Gy. The sharp beam was transformed into an approximately 9 cm diameter beam in the air with uniform dose distribution with the wobbler scattering method originally developed at Lawrence Berkeley National Laboratory (Chu et al. 1985).…”

Section: Methodsmentioning

confidence: 99%

Induction and isolation of pigmentation mutants of Porphyra yezoensis (Bangiales, Rhodophyta) by heavy‐ion beam irradiation

Niwa

Hayashi

Abe

et al. 2009

Phycological Research

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The present study describes the isolation of pigmentation mutants of Porphyra yezoensis Ueda induced by heavy-ion beam irradiation for the first time. The gametophytic blades were irradiated with 12 C +6 ion beams within a dose range of 25-400 Gy. From the survival rate and cell growth of the irradiated blades, it is suggested that a dose of 150 Gy or less is suitable to induce mutation for the isolation of mutants of P. yezoensis. After irradiation, red, green and deep reddish brown-colored gametophytic blades developed from archeospores that were released from each of the mutated cell clusters of the respective different colors, and the red mutant strain (IBY-R1) and green mutant strain (IBY-G1) were established as a conchocelis colony in culture. Blades of the mutants were characterized by their growth and photosynthetic pigment contents compared with those of the wild-type. From these results, it is clear that heavy-ion beam mutagenesis will be an effective tool for genetic and breeding studies of Porphyra, and also for other algal research.

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Section: Methodsmentioning

confidence: 99%

Induction and isolation of pigmentation mutants of Porphyra yezoensis (Bangiales, Rhodophyta) by heavy‐ion beam irradiation

Niwa

Hayashi

Abe

et al. 2009

Phycological Research

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“…The wobbler magnet power supplies, which provide sinusoidal currents, are easy to construct and reliable. 337 The pertinent parameters to obtain flat fields are constant spill intensity, precise wobble radii and correct particle-number fractions at various radii.…”

Section: Iic2a Rotating Dipolementioning

confidence: 99%

Instrumentation for treatment of cancer using proton and light-ion beams

Chu

Ludewigt

Renner

1993

Review of Scientific Instruments

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285

186

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Clinical trials using accelerated heavy charged-particle beams for treating cancer and other diseases have been performed for nearly four decades. Recently there have been worldwide efforts to construct hospital-based medically dedicated proton or light-ion accelerator facilities. To make such accelerated heavy charged-particle beams clinically useful, specialized instruments must be developed to modify the physical characteristics of the particle beams in order to optimize their biological and clinical effects. This article reviews the beam modifying devices and associated dosimetric equipment developed specifically for controlling and monitoring the clinical beams.

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“…Adequate uniformity and sharp falloff can be obtained using several concentric circular sweeps, from varying the sinusoidal driving voltage. Such a system can achieve ±2% uniformity over a 30 cm diameter field [28], which is substantially larger than is required for IsoDAR. Spreading the beam in this fashion reduces the power density on the target to about 2 kW/cm 2 .…”

Section: The Beam Transport Linementioning

confidence: 99%

Cost-effective Design Options for IsoDAR

Adelmann,

Alonso,

Barletta

et al. 2012

Preprint

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This whitepaper reviews design options for the IsoDAR electron antineutrino source. IsoDAR is designed to produce 2.6 × 10 22 νe per year with an average energy of 6.4 MeV, using isotope decay-at-rest. Aspects which must be balanced for cost-effectiveness include: overall cost; rate and energy distribution of the νe flux and backgrounds; low technical risk; compactness; simplicity of underground construction and operation; reliability; value to future neutrino physics programs; and value to industry. We show that the baseline design outlined here is the most cost effective.

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Wobbler Facility for Biomedical Experimenis at the Bevalac

Cited by 16 publications

References 2 publications

Induction and isolation of pigmentation mutants of Porphyra yezoensis (Bangiales, Rhodophyta) by heavy‐ion beam irradiation

Induction and isolation of pigmentation mutants of Porphyra yezoensis (Bangiales, Rhodophyta) by heavy‐ion beam irradiation

Instrumentation for treatment of cancer using proton and light-ion beams

Cost-effective Design Options for IsoDAR

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