WNT6 affects the prognosis of pediatric acute myeloid leukemia through regulation of Wnt signaling pathway activity
Yu Zhang,
Nadan Lu,
Yuanfang Li
et al.
Abstract:Purpose Pediatric acute myeloid leukemia (AML) is associated with a dismal prognosis, underscoring the urgent need to identify potential biomarkers that can aid in the management of pediatric AML patients.
Methods The adult AML dataset GSE201492 was partitioned into distinct prognostic groups following the identification of key genes through the screening of differentially expressed genes, enrichment analysis, and protein-protein interaction (PPI) analysis. Subsequently, these key genes were validated in the p… Show more
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