Abstract:Background: Jian-Gan-Xiao-Zhi decoction (JGXZ) is a formula of traditional Chinese medicine to treat patients with NAFLD. Thus, the study aimed to analyze the mechanism of drug serum of JGXZ in adipocytes and detect the main components of JGXZ in rat serum.Methods: The 3T3-L1 preadipocytes were used to establish IR adipocytes model. The lipid accumulation in adipocytes was detected by oil red O staining. After JGXZ treatment, glucose consumption, TC and TG were analyzed by corresponding kits. ROS levels were m… Show more
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