WITHDRAWN: Endorectal MRI accuracy in auguring tumour location, tumour extent, capsular perforation and seminal vesicle invasion of prostate cancer in north-African men

Janane, A.; Hajji, F.; Ismail, T. Ould; Elondo, J.C.; Ghadouane, M.; Ameur, A.; Abbar, M.

doi:10.1016/j.ejrad.2010.12.015

Cited by 3 publications

(9 citation statements)

References 19 publications

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…Even-Sapir et al fanden an einem Kollektiv von 23 Patienten für die konventionelle Ganzkörperskelettszintigrafie lediglich eine Sensitivität von 70 % und eine Spezifität von 57 % [29]. Für die 18 F-Fluorid-PET / CT hingegen ergab sich in derselben Untersuchung ein signifikanter Unterschied hinsichtlich der Sensitivität (100 %) und Spezifität (100 %), wobei einschränkend zu sagen ist, dass als Referenz lediglich andere bildgebende Verfahren herangezogen wurden und nur bei einem von 23 Patienten mit 18 Wertigkeit der Cholin-PET / CT im PSA-Rezidiv nach definitiver Therapie ! Nach radikaler Prostatektomie oder Radiatio der Prostata manifestiert sich in 20-50 % der Fälle innerhalb von 10 Jahren ein Tumorrezidiv [32,33].…”

Section: Beurteilung Knochenmetastasen (M-staging)unclassified

“…Die PET / CT als funktionell-bildgebendes Verfahren bietet zusätzlich zur morphologischen Darstellung die Möglich-keit, Tumorzellen anhand ihrer spezifischen Eigenschaften auf molekularer Ebene zu erkennen. Neben anderen Tracern, wie 18 F-Fluordesoxyglucose [36], 11 C-Acetat [37], und 18 F-FACBC [38] kamen in den bisherigen Untersuchungen vor allem 11 C-und 18 F-markierte Cholinderivate in der Rezidivdiagnostik des PCA zum Einsatz. Es zeigen sich dabei sehr heterogene Ergebnisse, wobei für die Cholin-PET / CT je nach Studie eine Sensitivität zwischen 38 und 98 % und eine Spezifität zwischen 40 und 100 % angegeben wird [39][40][41][42][43].…”

Section: Beurteilung Knochenmetastasen (M-staging)unclassified

See 1 more Smart Citation

Diagnostische Wertigkeit der Cholin-PET / CT bei Patienten mit Prostatakarzinom

Zengerling¹,

Schrader²,

Schrader³

et al. 2011

Aktuel Urol

View full text Add to dashboard Cite

The choline-positron emissiontomography / computed tomography (choline-PET / CT) is a widely used imaging method for prostate cancer. This review concentrates on the relevance of choline-PET / CT for primary diagnosis, staging and re-staging of prostate cancer and highlights possible -applications in clinical practice. Therefore, we performed a systematic literature research via Pubmed and Medline database for original articles, reviews and editorials on choline-PET / CT and prostate cancer. Choline-PET / CT should not be routinely used for primary diagnosis of prostate cancer due to a lack of data. With regard to the definition of the local tumour extent (T-stag-ing) choline-PET / CT plays only a minor role, in contrast, for the evaluation of lymph node involvement it has a high positive predictive value and is equal to conventional scintigraphy in detecting bone metastases. Moreover, in cases of biochemical relapse following local therapy, choline-PET / CT seems to be appropriate for differentiating between local recurrence and systemic prostate cancer metastasis, particularly when patients are selected by defined criteria (PSA value > 1.0 ng / mL and / or PSAdt < 6 months and / or Gleason score > 7 and / or primary radiotherapy). The non-critical routine use of choline-PET / CT for patients with prostate cancer cannot be recommended, and this not only because of its high costs. It should be applied to definite clinical questions after thorough selection of appropriate patients.

show abstract

Section: Beurteilung Knochenmetastasen (M-staging)unclassified

Diagnostische Wertigkeit der Cholin-PET / CT bei Patienten mit Prostatakarzinom

Zengerling¹,

Schrader²,

Schrader³

et al. 2011

Aktuel Urol

View full text Add to dashboard Cite

show abstract

“…Kim et al suggested the presence of VSI when there was a low intensity sign causing dilation and an asymmetric gland (18). Janane et al identified the VSI as the focal shortening of the wall or the presence of low intensity sign inside the vesicles (14). Brajtford et al only informed presence or absence of VSI (17).…”

Section: )mentioning

confidence: 99%

“…Janane et al included a particular north-african population and didn't mention the categorization of the population according to extra-prostatic risk of the disease (14). Kim et al excluded low risk patients and included only high or intermediate risk patients (18).…”

Section: )mentioning

confidence: 99%

See 1 more Smart Citation

Magnetic Resonance Image in the diagnosis and evaluation of extra-prostatic extension and involvement of seminal vesicles of prostate cancer: a systematic review of literature and meta-analysis

et al. 2013

View full text Add to dashboard Cite

Objective: Systematic review of literature and meta-analysis to evaluate the results of magnetic resonance image 1.5T with endorectal coil in the diagnosis and evaluation of extra-prostatic extension and involvement of seminal vesicles of prostate cancer, compared to the histopathological results of the radical prostatectomy specimen. Materials and Methods: It was conducted a systematic review of literature and meta--analyses of all studies data published after 2008. In those studies, the patients with prostate cancer with indication to radical prostatectomy were submitted to magnetic resonance image (MRI) at pre-operatory period and the results were compared to those of histopathological studies after the surgery. The selected terms for research included prostate cancer, magnetic resonance, radical prostatectomy, and prostate cancer diagnosis, in the databases EMBASE, LILACS, PUBMED/MEDLINE and Cochrane Library. The data were collected using a specific qualitative instrument and the meta-analysis data were presented in the forest plot graphics, homogeneity test and sROC curves and funnel plot. Results: A total of seven studies were included, with a total of 603 patients. Among these studies, six evaluated the value of MRI for the detection of prostate cancer, and the median sensitivity of meta-analysis was 0.6 and specificity 0.58, but with heterogeneity among the studies. Three studies evaluated extra-prostatic extension with a median sensitivity of 0.49, specificity 0.82 and heterogeneity only for sensitivity. Three studies evaluated invasion of seminal vesicles, with median sensitivity of 0.45 and specificity 0.96, with heterogeneity in both analysis. Conclusion: Magnetic resonance of 1.5T with endocoil showed low values of sensitivity and specificity for the diagnosis and staging of prostate cancer. The reviewed studies showed a significant heterogeneity among them. The best observed result was MRI specificity for invasion of seminal vesicles. More studies are necessary to evaluate new techniques and parameters before recommending the routine use of MRI in clinical practice.

show abstract