WITHDRAWN: Advances in pharmaceutical development of modified-release drug formulations and products

Abstract

The ongoing need to provide greater therapeutic efficacy and reduced side effects has accelerated the interest in modified release oral dosage forms design and development. Up to now, being developed by both formulation design strategy and manufacturing process, the modified release is one of the most common forms for oral delivery. From the need of meeting the ongoing challenges in current drug delivery, a variety of modified release platforms have been developed. This review aims to summarise recent literature with an emphasis on types of various controlled release dosage forms with reference made to the commercial excipients and polymers currently used during the formulation development.