With Nickel

Hoffman, Morton Z.

doi:10.1002/9780470145302.ch125

Cited by 2 publications

(3 citation statements)

References 25 publications

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“…The most prominent feature at around E cm = 0.81 MeV corresponds to a known J π =(9/2) + state in 21 Ne at an excitation energy of 8.155(1) MeV [25]. This resonance appears to be of comparable strength in both gamma and neutron channels [10,14].…”

Section: Resultsmentioning

confidence: 99%

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A direct measurement of the 17O(α,γ)21Ne reaction in inverse kinematics and its impact on heavy element production

et al. 2019

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During the slow neutron capture process in massive stars, reactions on light elements can both produce and absorb neutrons thereby influencing the final heavy element abundances. At low metallicities, the high neutron capture rate of 16 O can inhibit s-process nucleosynthesis unless the neutrons are recycled via the 17 O(α,n) 20 Ne reaction. The efficiency of this neutron recycling is determined by competition between the 17 O(α,n) 20 Ne and 17 O(α, γ) 21 Ne reactions. While some experimental data are available on the former reaction, no data exist for the radiative capture channel at the relevant astrophysical energies.The 17 O(α, γ) 21 Ne reaction has been studied directly using the DRAGON recoil separator at the TRIUMF Laboratory. The reaction cross section has been determined at energies between 0.6 and 1.6 MeV E cm , reaching into the Gamow window for core helium burning for the first time. Resonance strengths for resonances at 0.63, 0.721, 0.81 and 1.122 MeV E cm have been extracted. The experimentally based reaction rate calculated represents a lower limit, but suggests that significant s-process nucleosynthesis occurs in low metallicity massive stars.PACS numbers 26.20. Kn, 25.40.Lw

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Section: Resultsmentioning

confidence: 99%

“…There is a known J π = 3/2 + state of total width 8 keV [25] at 8.069 MeV (E cm = 0.721 MeV). This state contributes to both the 0.695 and 0.748 MeV data points, with each measurement covering approximately half of the relevant yield.…”

Section: Resultsmentioning

confidence: 99%

A direct measurement of the 17O(α,γ)21Ne reaction in inverse kinematics and its impact on heavy element production

et al. 2019

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“…Newer peptide and protein delivery strategies for indications in hair therapy range from immunization approaches for tolerance induction in alopecia areata (44) to delivery of PTH-based compounds in chemotherapy-induced alopecia (45), and even non-invasive delivery of other macromolecules such as superoxide dismutase (46). As early reports on topical application of vectors using liposomes (47)(48)(49), efforts to modulate gene activity or correct genes are very actively being pursued by topical delivery of oligonucleotides, DNA vectors, siRNA and vectors. For example, delivery of mRNA and siRNA by different means including microneedles resulted in gene knock-down or reduced gene expression (50,51).…”

Section: 'Novel' Deliverymentioning

confidence: 99%

Selective hair therapy: bringing science to the fiction

Vogt

Blume-Peytavi

2014

Experimental Dermatology

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Investigations on carrier-based drug delivery systems for higher selectivity in hair therapy have clearly evolved from dye release and model studies to highly sophisticated approaches, many of which specifically tackle hair indications and the delivery of hair-relevant molecules. Here, we group recent hair diseaseoriented work into efforts towards (i) improved delivery of conventional drugs, (ii) delivery of novel drug classes, for example biomolecules and (iii) targeted delivery on the cellular/molecular level. Considering the solid foundation of experimental work, it does not take a large step outside the current box of thinking to follow the idea of using large carriers (>500 nm, unlikely to penetrate as a whole) for follicular penetration, retention and protection of sensitive compounds. Yet, reports on particles <200 nm being internalized by keratinocytes and dendritic cells at sites of barrier disruption (e.g., hair follicles) combined with recent advances in nanodermatology add interesting new facets to the possibilities carrier technologies could offer, for example, unprecedented levels of selectivity. The authors provide thoughtprovoking ideas on how smart delivery technologies and advances in our molecular understanding of hair pathophysiology could result in a whole new era of hair therapeutics. As the field still largely remains in preclinical investigation, determined efforts towards production of medical grade material and truly translational work are needed to demonstrate surplus value of carrier systems for clinical applications.

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With Nickel

Cited by 2 publications

References 25 publications

A direct measurement of the 17O(α,γ)21Ne reaction in inverse kinematics and its impact on heavy element production

A direct measurement of the 17O(α,γ)21Ne reaction in inverse kinematics and its impact on heavy element production

Selective hair therapy: bringing science to the fiction

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