With Corona Virus, We Get Sick; With the Weapon of Science and Engineering, We Fight Back?

Jiang, Qinglong; Guo, Zhanhu; Yang, Guang; Wujick, Evan; Gu, Hongbo

doi:10.30919/es8d916

Cited by 3 publications

(4 citation statements)

References 4 publications

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“…In recent years, there has been a lot of news about outbreaks and diseases in the world, which negatively affects human life, including coronavirus, influenza, hepatitis, Salmonella, and Escherichia coli infections. [1][2][3] Therefore, consumers focused extremely on medical products and then, as a natural consequence, the use of textiles on medical, hygiene, and health care fields has become significantly widespread with new antimicrobials, functional fibers, new chemical finishes, and technologies. 4 As a result of all these, Medical Textiles Market is estimated to be valued at 10.5 billion USD by 2022, 5 and medical textiles are one of the most dynamically growing sectors because of changes in demographics, aging, growth of population, global warming, and health risks.…”

Section: Introductionmentioning

confidence: 99%

Triclosan applications for biocidal functionalization of polyester and cotton surfaces

Orhan

2020

Journal of Engineered Fibers and Fabrics

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For 20 years, antibacterial functionalization has been one of the most attractive research fields in the textile industry. Nowadays, globalization has spread the microorganisms everywhere and produced many epidemics and pandemics such as smallpox, cholera, tuberculosis, yellow fever, Spanish flu, and coronavirus. The textile materials treated with triclosan would be a strong alternative to obtain antibacterial function against microorganisms for the medical applications, such as face masks, lab coats, and wound dresses. This study aimed to investigate the characterization, antibacterial properties, and durability of triclosan on polyester, polyester/cotton, and cotton surfaces. The pure triclosan and presence of triclosan in solutions were detected by gas chromatography–mass spectrometry chromatograms. It can be seen that surfaces were homogeneously covered by triclosan on scanning electron microscope micrographs, and there were new bands on Fourier transform infrared spectra after treatments. Large inhibition zones around all surfaces were observed, and antibacterial activity slightly increased depending on increasing chemical concentrations. The samples demonstrated strong biocidal activity to bacteria for 3 h. They lost their antibacterial properties after washing, but they showed good antibacterial (bactericidal) properties and satisfactory durability to washes. The results show that triclosan is a highly effective and durable chemical on polyester and cotton surfaces for medical textile applications.

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Section: Introductionmentioning

confidence: 99%

Triclosan applications for biocidal functionalization of polyester and cotton surfaces

Orhan

2020

Journal of Engineered Fibers and Fabrics

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“…6 In addition to bacteria, there are also viruses that seriously threaten human health, for example COVID-19. [7][8][9] COVID-19 is mainly spread by direct transmission, aerosol transmission, and contact transmission. Unlike a bacterial infection, but viral infection makes a big difference.…”

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confidence: 99%

Antibacterial Mechanism of Dihydrotanshinone I

Zhao

Wei

et al. 2021

Natural Product Communications

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The antimicrobial activity and the underlying action mechanisms of dihydrotanshinone I against Staphylococcus aureus, methicillin-resistant Staphylococcus aureus, extended-spectrum beta-lactamases Staphylococcus aureus were investigated with Kleihauer-Betke (K-B) test. The antibacterial mechanisms of dihydrotanshinone I were investigated by monitoring the changes in electric conductivity, concentration of AKP, protein content, and patterns of protein electrophoretic bands in sodium dodecyl sulfate-polyacrylamide gel electrophoresis (SDS-PAGE). The antibacterial rings showed that antimicrobial activity of dihydrotanshinone I at 18 mM was stronger to Staphylococcus aureus than to methicillin-resistant Staphylococcus aureus and extended-spectrum beta-lactamases Staphylococcus aureus. The minimum inhibitory concentration (MIC) and IC50 values showed that dihydrotanshinone I had the strongest inhibitory activity against S. aureus (MIC = 280 µM, IC50 = 874 ± 0.01 µM, respectively). Dihydrotanshinone I could increase the electric conductivity, concentration of alkaline phosphatase (AKP) and protein content. The patterns of protein bands in SDS-PAGE were changed obviously. Dihydrotanshinone I also significantly inhibited S. aureus, methicillin-resistant S. aureus, and extended-spectrum beta-lactamases S. aureus, indicating that dihydrotanshinone I can damage the structures of cell wall and cell membrane to increase permeability of cell membrane and release of cell components. Dihydrotanshinone I could influence the synthesis of bacterial protein, destroy the protein, or reject the anabolism or expression of the protein, and finally lead to the loss of normal physiological function of bacteria.

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“…It has been a year since the outbreak of COVID-19 virus pandemic in the world. [1] A long period of chaos, it is a great pleasure to see that we are on the correct track after wasting almost a whole year. Humans need science and technology in fighting such outbreaks, instead of pride and prejudice.…”

mentioning

confidence: 99%

“…As mentioned before, scientists will never fight alone. [1] Thanks to the doctors, nurses, biologist, chemists, engineers, etc. From the time the pandemic commenced, scientists at all levels of expertise were at work and now everybody can notice the outcome (COVID-19 vaccine) showing directly how science and technology are beneficial.…”

mentioning

confidence: 99%