Electrochemiluminescence (ECL) is an important electrochemistry analytical method with high sensitivity, low backgrounds, excellent controllability and rapid determination. The State Key Laboratory of Electroanalytical Chemistry has been working on ECL for more than two decades. We introduce the main research results of our institute in the field of novel ECL reagent, highly efficient coreactant, new kinds of electrodes, nanoparticle catalyst, capillary electrophoresis/microfludic chip on ECL analysis and ECL device.