Wireless capsule endoscopyAugust 2002

Ginsberg, Gregory G.; Barkun, Alan N.; Bosco, John J.; Isenberg, Gerard; Nguyen, Cuong C.; Petersen, Bret T.; Silverman, William B.; Slivka, Adam; Taitelbaum, Greta

doi:10.1016/s0016-5107(02)70106-5

Cited by 121 publications

(53 citation statements)

References 7 publications

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“…Although wireless capsule endoscopy theoretically allows visualization of the lumen of the entire small intestine, the actual extent of lumen visualized has not been studied systematically. The field of view from the capsule is only 140 • , such that some proportion of the lumen may be in a "blind spot" [4]. In addition, the view can be obscured by the presence of bubbles, food and other debris, and bile pigments, especially when concentrated in the ileum, may greatly absorb the light and impair visualization.…”

Section: Introductionmentioning

confidence: 99%

Visualization of the Small Intestine Using Capsule Endoscopy in Healthy Subjects

2007

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The actual extent of lumen visualized by capsule endoscopy has not been studied systematically. Volunteers were randomized to receive a bowel preparation (prep) consisting of an isotonic solution containing polyethylene glycol and simethicone. The prep (200 ml) was given 30 min before the capsule. The capsule was taken with 100 ml of prep and 100 ml of water; 100 ml of prep was given 45 and 75 min later. The control administration was 100 ml of water and no simethicone. Forty percent of all frames taken in the small bowel were examined and individually scored for circumference, bubbles, debris, and lighting. Nine volunteers were studied twice. Only 50% of the circumference is seen normally. The prep improved the circumference to 62.5% as well as decreasing luminal debris and bubbles and improving the lighting. We conclude that the prep solution improved small bowel visualization, however, improvements are still needed to optimize visualization.

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Section: Introductionmentioning

confidence: 99%

Visualization of the Small Intestine Using Capsule Endoscopy in Healthy Subjects

2007

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“…Furthermore, capsule endoscopy is known to be significantly superior to push enteroscopy in terms of diagnostic yield for patients with obscure GI bleeding (8). Other potential indications for capsule endoscopy include surveillance in patients with polyposis, inflammatory bowel disease, suspected enteric tumors, or infiltrative lesions (9). However, capsule endoscopy has limitations, for example, it is not possible to take biopsy samples, there is no control over the capsule's movements, it is not known with precision where the capsule is in the small bowel, and it is impossible to determine the number of lesions if they have similar appearances (10).…”

Section: Discussionmentioning

confidence: 99%

Ileal Inflammatory Fibroid Polyp: A Rare Cause of Obscure Gastrointestinal Bleeding Diagnosed by Wireless Capsule Endoscopy

et al. 2006

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KEY WORDS: capsule endoscopy; inflammatory fibroid polyp; gastrointestinal bleeding.Obscure gastrointestinal (GI) bleeding is defined as bleeding of an unknown origin that persists or recurs after a negative initial or primary endoscopy (upper and/or lower GI endoscopy) (1). The source of bleeding is frequently located in the small bowel, which can only be partially examined by conventional endoscopy. Radiographic and radioisotopic techniques for small bowel evaluation are relatively insensitive for small lesions and in the absence of brisk bleeding, and other techniques are complex, are poorly tolerated, and carry a moderate risk of complications (2, 3). A painless, swallowable capsule containing a video device (Given Imaging, Inc., Yoqneam, Israel) was recently developed in order to record photographic images of the small bowel during normal peristaltic motion (4).We present here the case of a patient with an inflammatory fibroid polyp as the focus of small bowel bleeding which was diagnosed by wireless capsule endoscopy. CASE REPORTA 48-year-old man presented with a 3-month history of dizziness and intermittent melena. He did not complain of abdominal pain, hematemesis, hematochezia, or weight loss. On admission, his vital signs were stable and no anemic conjunctivae were observed. Physical examination revealed no tenderness or mass on abdomen. The results of laboratory tests were as follows: hemoglobin, 7.7 g/dl; white blood cell count, 4900/mm 3 ; platelets, 210,000/mm 3 ; total protein, 7.5 g/dl; albumin, 4.1 g/dl; serum iron, 12 μg/dl; total iron binding capacity, 371 μg/dl; ferritin, 3 μg/L; and fecal occult blood test, positive. Esophagogastroduodenoscopy was normal and colonoscopy revealed old blood in the terminal ileum without any focus of active bleed-

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“…After ingestion of the capsule, the patients were allowed nothing orally for 4 h and were observed for 8 h at the study site. After 8 h, the sensor array and recording device were removed, and following upload to the digital processor, the images and the movie clip of the small intestinal passage were evaluated [22].…”

Section: Capsule Endoscopymentioning

confidence: 99%

Capability of Capsule Endoscopy in Detecting Small Bowel Ulcers

Ersoy¹,

Harmanci

Aydınlı

et al. 2008

Dig Dis Sci

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Capsule endoscopy (CE) has proved to be the preferred modality for mucosal pathologies of the small bowel. We evaluated the capability of CE for detecting small bowel ulcers and the contribution of CE in establishing the diagnosis. From a total of 66 patients who had undergone normal upper and lower endoscopy and small bowel follow-through, CE revealed previously undiagnosed ulcer(s) in the small intestines of 22 patients. Final diagnoses of the ulcers of these 22 patients were Crohn's disease (n = 9), Behçet's disease (n = 2), nonspecific jejunoileitis (n = 2), vasculitis (n = 1), gastrointestinal stromal tumor (n = 1), adenocarcinoma (n = 1), lymphoma (n = 1), multiple myeloma (n = 1), Meckel's diverticulum (n = 1) and unknown (n = 3). Capsule endoscopy was extremely useful in establishing the diagnosis. In this study, proximal, distal and diffuse small bowel ulcers were determined at rates of 27.3, 59.0 and 13.7%, respectively. Capsule endoscopy facilitated the detection and assessment of ulcerated mucosal lesions located in the small bowel.

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Wireless capsule endoscopyAugust 2002

Cited by 121 publications

References 7 publications

Visualization of the Small Intestine Using Capsule Endoscopy in Healthy Subjects

Visualization of the Small Intestine Using Capsule Endoscopy in Healthy Subjects

Ileal Inflammatory Fibroid Polyp: A Rare Cause of Obscure Gastrointestinal Bleeding Diagnosed by Wireless Capsule Endoscopy

Capability of Capsule Endoscopy in Detecting Small Bowel Ulcers

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