In this paper ATLANTIS is described-a network of actual six German universities exchanging courses in varying blended learning scenarios over the Internet. Basic goals are to broaden study programs at the participating locations in MIS, to decrease the number of different courses a professor has to offer as part of her/his teaching load and to enhance flexibility of students who get the chance to take courses at individual convenient times and locations. ATLANTIS courses are running on a centralized Learning Management System (LMS) (Coates, James, & Baldwin, 2005) with interfaces to each local LMS of the participating universities. In an initial project of two years the technical infrastructure and E-Learning courses have been developed and an organization has been established. Since then the network is in a state of regular use. The case study focuses on organizational issues and lessons learned in 4 years of development and operation.